| Weight | 363.502 g/mol |
|---|---|
| Formula | C20H33N3O3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 7 |
Talinolol (57460-41-0)
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- Induction of Pglycoprotein by rifampin increases intestinal secretion of talinolol in human beings: A new type of drug/drug interaction (Clinical Pharmacology & Therapeutics, 2000)
- The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol (Clinical Pharmacology & Therapeutics, 2002)
- Oral bioavailability of digoxin is enhanced by talinolol: Evidence for involvement of intestinal Pglycoprotein (Clinical Pharmacology & Therapeutics, 2000)
- Grapefruit juice ingestion significantly reduces talinolol bioavailability (Clinical Pharmacology & Therapeutics, 2005)
- P-glycoprotein inhibitor erythromycin increases oral bioavailability of talinolol in humans. (Principles and Practice of Constraint Programming, 2000)
- Carbamazepine regulates intestinal P-glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans (Clinical Pharmacology & Therapeutics, 2004)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)(C)NCC(COC1=CC=C(C=C1)NC(=O)NC2CCCCC2)O
-
InChIKeyMXFWWQICDIZSOA-UHFFFAOYSA-N
- Pubchem - Talinolol
- Wikipedia - talinolol
Talinolol is a beta blocker.
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Synthesis
Reactant
+
CYCLOHEXYLAMINE
(Thiourea)
Reactant
+
CHLOROCYCLOHEXANE
(Alkylation of primary amines)
Reactant
+
SCHEMBL6643064
(Schotten-Baumann amide from acid)
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