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MIDODRINE HYDROCHLORIDE
Weight290.747 g/mol
FormulaC12H19ClN2O4
Hydrogen Acceptors5
Hydrogen Donors3
Aromatic Rings1
Rotatable Bonds6

MIDODRINE HYDROCHLORIDE (43218-56-0)

Midodrine  ·  Midon  ·  ProAmatine

Score: #177 in Neurology , #785 in Neuroscience , #3456 in Biology , #4316 in Chemistry
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Alternate Names

  • Midodrine
  • Midon
  • ProAmatine
  • Amatine
  • Gutron
  • Midodrine Monohydrochloride
  • Midodrin
  • ST1085
  • ST 1085
  • ST-1085
  • SMILES
    COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O.Cl
  • InChIKey
    MGCQZNBCJBRZDT-UHFFFAOYSA-N

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Synthesis

Glycinamide  +  2-Chloro-1-(2,5-dimethoxyphenyl)ethan-1-ol (Alkylation of primary amines)
Reactant  +  2-Chloro-1,4-dimethoxybenzene (Grignard alcohol)
1,4-Dimethoxybenzene  +  Reactant (Friedel-Crafts alkylation)
Reactant  +  Methyl hydroperoxide (Dakin oxidation)
Synthesis of MIDODRINE HYDROCHLORIDE ›

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