4-Methoxycinnamic acid (943-89-5, 830-09-1)

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Suppliers

• Sigma-Aldrich - 4-Methoxycinnamic acid
  25.00 - 158.50 USD
• Fisher Scientific - Search for 4-Methoxycinnamic acid
• TCI - 4-Methoxycinnamic acid
  38.00 - 122.00 USD

Most-cited Publications

• The purification and characterization of 4-hydroxy-3-methoxycinnamic (ferulic) acid esterase from Streptomyces olivochromogenes. (Microbiology, 1991)
• Examination of the Chemical Composition of Propolis 2. Isolation and Identification of 4-Hydroxy-3-Methoxycinnamic Acid (Ferulic Acid) from Propolis (Journal of Apicultural Research, 1973)
• Trans-4-hydroxy-3-methoxycinnamic acid (ferulic acid) inhibits the effect of androgens on the rat prostate (Cellular and Molecular Life Sciences, 1979)
• Complexes of the selected transition metal ions with 4-methoxycinnamic acid (Journal of Thermal Analysis and Calorimetry, 2012)
• Alpha Cyano-4-Hydroxy-3-Methoxycinnamic Acid Inhibits Proliferation and Induces Apoptosis in Human Breast Cancer Cells (PLOS ONE, 2013)
• Polyamine levels in various tissues of rats treated with 3-hydroxy-4-methoxycinnamic acid and 3,4-dimethoxycinnamic acid. (Anti-Cancer Drugs, 1996)

Areas of Application

Safety

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Trends

Alternate Names

• 4-methoxycinnamate, potassium salt
• 4-methoxycinnamate, sodium salt
• 4-methoxycinnamate, zinc salt
• 4-methoxycinnamate, (E)-isomer
• 4-methoxycinnamate, (Z)-isomer
• 4-methoxycinnamate, magnesium salt
• 4-methoxycinnamate
• 4-methoxycinnamate, aluminum salt
• E-p-methoxycinnamic acid
• 4-methoxycinnamate, calcium salt
• 4-methoxycinnamate, zirconium salt
• SMILES
  COC1=CC=C(C=C1)C=CC(=O)O
• InChIKey
  AFDXODALSZRGIH-UHFFFAOYSA-N

External Links

• Pubchem - 4-Methoxycinnamic acid
• Wikipedia - 4-methoxycinnamic acid

Synthesis

glyoxylic acid  +  4-Methoxybenzyl chloride (Wittig)

Acrylic Acid  +  4-Chloroanisole (Heck terminal vinyl)

4-Methoxybenzaldehyde  +  ACETIC ANHYDRIDE (Perkin reaction)

4-Formylcinnamic acid  +  Methyl hydroperoxide (Dakin oxidation)

(Z)-3-BROMOACRYLIC ACID  +  4-Chloroanisole (Stille)

Reactant  +  dimethyl sulfide (Corey-Kim oxidation of secondary alcohols)

Reactant  +  1-Hydroxy-1,2-benziodoxol-3(1H)-one 1-oxide (Nicolaou IBX dehydrogenation)

Synthesis of 4-Methoxycinnamic acid ›

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4-Methoxycinnamic acid

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