| Weight | 276.207 g/mol |
|---|---|
| Formula | C13H19Cl2NO |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 3 |
Bupropion hydrochloride (34841-36-6, 31677-93-7)
Bupropion · Wellbutrin · Quomen
Score:
#547 in Neuroscience
,
#2468 in Biology
,
#3079 in Chemistry
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- A controlled trial of sustained - Release bupropion, a nicotine patch, or both for smoking cessation (The New England Journal of Medicine, 1999)
- Efficacy of Varenicline, an 42 Nicotinic Acetylcholine Receptor Partial Agonist, vs Placebo or Sustained-Release Bupropion for Smoking Cessation A Randomized Controlled Trial (JAMA, 2006)
- A Comparison of Sustained-Release Bupropion and Placebo for Smoking Cessation (The New England Journal of Medicine, 1997)
- Varenicline, an 42 Nicotinic Acetylcholine Receptor Partial Agonist, vs Sustained-Release Bupropion and Placebo for Smoking Cessation A Randomized Controlled Trial (JAMA, 2006)
- Bupropion-SR, Sertraline, or Venlafaxine-XR after Failure of SSRIs for Depression (The New England Journal of Medicine, 2006)
- Bupropion: a review of its mechanism of antidepressant activity (The Journal of Clinical Psychiatry, 1995)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Bupropion
- Wellbutrin
- Quomen
- Zyban (Anti-Smoking)
- Bupropion, (+-)-Isomer
- Zyntabac
- (+-)-1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone
- Bupropion Hydrochloride, (+-)-Isomer
- Amfebutamone
-
SMILESCC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C.Cl
-
InChIKeyHEYVINCGKDONRU-UHFFFAOYSA-N
- Pubchem - Bupropion hydrochloride
- Wikipedia - bupropion hydrochloride
Bupropion is a medication primarily used as an antidepressant and smoking cessation aid. It is marketed as Wellbutrin and Zyban among other trade names. It is one of the most frequently prescribed antidepressants in the United States and Canada, although in many countries this is an off-label use.
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Most-cited Publications
Areas of Application
Safety
Trends
Alternate Names
External Links
Synthesis
2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-ol
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
CHLOROBENZENE
+
Reactant
(Friedel-Crafts acylation)
Reactant
+
1,3-DICHLOROBENZENE
(Grignard carbonyl)
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Bupropion hydrochloride
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