| Weight | 316.316 g/mol |
|---|---|
| Formula | C17H27Cl2N |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 5 |
SIBUTRAMINE HCl (84485-00-7)
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- Effect on radiolabelled-monoamine uptake in vitro of plasma taken from healthy volunteers administered the antidepressant sibutramine HCl (Psychopharmacology, 1990)
- Effect of sibutramine HCl on cardiac hERG K+ channel (Molecular and Cellular Biochemistry, 2009)
- Electrophysiological safety of sibutramine HCl (Human & Experimental Toxicology, 2008)
- Conductometric determination of sibutramine HCl, sumatriptan succinate and lomefloxacine HCl and the solubility products of their ion associates with molybdophosphoric acid (European Journal of Chemistry, 2013)
- DEVELOPMENT OF ANALYTICAL METHOD FOR IDENTIFICATION OF SIBUTRAMINE HCL IN TRADITIONAL MEDICINE USING SOLID PHASE EXTRACTION HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (Asian Journal of Pharmaceutical and Clinical Research, 2016)
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SMILESCC(C)CC(C1(CCC1)C2=CC=C(C=C2)Cl)N(C)C.Cl
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InChIKeyUWAOJIWUVCMBAZ-UHFFFAOYSA-N
- Pubchem - SIBUTRAMINE HCl
- Wikipedia - sibutramine hydrochloride
Sibutramine, formerly sold under the brand name Meridia among others, is an appetite suppressant which has been discontinued in many countries. Until 2010, it was widely marketed and prescribed as an adjunct in the treatment of obesity along with diet and exercise. It has been associated with increased cardiovascular events and strokes and has been withdrawn from the market in several countries and regions including Australia, Canada, China, the European Union, Hong Kong, India, Mexico, New Zealand, the Philippines, Thailand, the United Kingdom, and the United States.
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