| Weight | 508.645 g/mol |
|---|---|
| Formula | C23H36N6O5S |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 5 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 9 |
argatroban (121785-71-5, 121785-72-6)
Score:
#175 in Neurology
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#775 in Neuroscience
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#3409 in Biology
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#4256 in Chemistry
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- Sigma-Aldrich - Search for argatroban
- Fisher Scientific - Search for argatroban
- TCI - Search for argatroban
- Argatroban Anticoagulant Therapy in Patients With Heparin-Induced Thrombocytopenia (Circulation, 2001)
- Argatroban Anticoagulation in Patients With Heparin-Induced Thrombocytopenia (JAMA Internal Medicine, 2003)
- The pharmacokinetics and pharmacodynamics of argatroban: effects of age, gender, and hepatic or renal dysfunction. (Pharmacotherapy, 2000)
- College of American Pathologists Conference XXXI on laboratory monitoring of anticoagulant therapy: the clinical use and laboratory monitoring of low-molecular-weight heparin, danaparoid, hirudin and related compounds, and argatroban. (Archives of Pathology & Laboratory Medicine, 1998)
- Argatroban anticoagulation during percutaneous coronary intervention in patients with heparininduced thrombocytopenia (Catheterization and Cardiovascular Interventions, 2002)
- Novastan (brand of argatroban) : A small-molecule, direct thrombin inhibitor (Seminars in Thrombosis and Hemostasis, 1997)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1CCN(C(C1)C(=O)O)C(=O)C(CCCN=C(N)N)NS(=O)(=O)C2=CC=CC3=C2NCC(C3)C
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InChIKeyKXNPVXPOPUZYGB-UHFFFAOYSA-N
- Pubchem - argatroban
- Wikipedia - (21R)-argatroban anhydrous
Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. In 2000, argatroban was licensed by the Food and Drug Administration (FDA) for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT). In 2002, it was approved for use during percutaneous coronary interventions in patients who have HIT or are at risk for developing it.
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