| Weight | 490.626 g/mol |
|---|---|
| Formula | C24H34N4O5S |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 7 |
glimepiride (684286-46-2, 93479-97-1)
Amaryl · Amarel · Aventis brand of glimepiride
Score:
#826 in Biochemistry
,
#2229 in Biology
,
#2742 in Chemistry
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- Efficacy and Safety Comparison of Liraglutide, Glimepiride, and Placebo, All in Combination With Metformin, in Type 2 Diabetes: The LEAD (Liraglutide Effect and Action in Diabetes)-2 study (Diabetes Care, 2009)
- Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial (The Lancet, 2009)
- Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin in type 2 diabetes mellitus (LEAD-2 Met) (Diabetes Care, 2008)
- Comparison of Pioglitazone vs Glimepiride on Progression of Coronary Atherosclerosis in Patients With Type 2 Diabetes The PERISCOPE Randomized Controlled Trial (JAMA, 2008)
- Effect of pioglitazone compared with glimepiride on carotid intima-media thickness in type 2 diabetes : A randomized trial (JAMA, 2006)
- Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, in patients with type 2 diabetes mellitus inadequately controlled on glimepiride alone or on glimepiride and metformin (Diabetes, Obesity and Metabolism, 2007)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Amaryl
- Amarel
- Aventis brand of glimepiride
- Aventis Pharma brand of glimepiride
- Hoechst brand of glimepiride
- 1-(4-(2-(3-ethyl-4-methyl-2-oxo-3-pyrrolinecarboxamido)ethyl)phenylsulfonyl)-3-(4-methylcyclohexyl)urea
- Lacer brand of glimepiride
- Aventis Behring brand of glimepiride
- Roname
- HOE-490
- HOE 490
- glymepiride
-
SMILESCCC1=C(CN(C1=O)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCC(CC3)C)C
-
InChIKeyWIGIZIANZCJQQY-UHFFFAOYSA-N
- Pubchem - glimepiride
- Wikipedia - Glimepiride
Glimepiride (original trade name Amaryl) is an orally available medium-to-long-acting sulfonylurea antidiabetic drug. It is sometimes classified as either the first third-generation sulfonylurea, or as second-generation.
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Most-cited Publications
Areas of Application
Safety
Alternate Names
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Synthesis
1-(Benzenesulfonyl)-3-(4-methylcyclohexyl)urea
+
Reactant
(Friedel-Crafts alkylation)
Reactant
+
766-36-9
(Thiourea)
Reactant
+
766-36-9
(Schotten-Baumann amide from acid)
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glimepiride
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