| Weight | 308.378 g/mol |
|---|---|
| Formula | C16H24N2O4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 8 |
Bestatin (65391-42-6, 58970-76-6)
bestatin, (D-Leu)-(R-(R*,R*))-isomer · bestatin, (L-Leu)-(S-(R*,S*))-isomer, hydrochloride · bestatin, (L-Leu)-(R-(R*,R*))-isomer
Score:
#1213 in Biochemistry
,
#3042 in Biology
,
#3805 in Chemistry
"What do you need help with?"
LabBot
- Sigma-Aldrich - Bestatin280.00 USD
- Fisher Scientific - Search for Bestatin
- TCI - Search for Bestatin
- BESTATIN, AN INHIBITOR OF AMINOPEPTIDASE B, PRODUCED BY ACTINOMYCETES (The Journal of Antibiotics, 1976)
- Inhibition of aminopeptidases by amastatin and bestatin derivatives. Effect of inhibitor structure on slow-binding processes. (Journal of Medicinal Chemistry, 1984)
- Inhibition of aminopeptidase B and leucine aminopeptidase by bestatin and its stereoisomer. (Archives of Biochemistry and Biophysics, 1976)
- Structure determination and refinement of bovine lens leucine aminopeptidase and its complex with bestatin (Journal of Molecular Biology, 1992)
- Synthesis and structure-activity relationships of bestatin analogues, inhibitors of aminopeptidase B. (Journal of Medicinal Chemistry, 1977)
- Enhancement of delayed-type hypersensitivity by bestatin, an inhibitor of aminopeptidase B and leucine aminopeptidase. (The Journal of Antibiotics, 1976)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - bestatin, (D-Leu)-(R-(R*,R*))-isomer
- bestatin, (L-Leu)-(S-(R*,S*))-isomer, hydrochloride
- bestatin, (L-Leu)-(R-(R*,R*))-isomer
- bestatin, (L-Leu)-(R-(R*,S*))-isomer
- bestatin, (D-Leu)-(R-(R*,S*))-isomer
- bestatin, (D-Leu)-(S-(R*,S*))-isomer
- 3-amino-2-hydroxy-4-phenylbutyryl-L-leucine
- bestatin, (L-Leu)-(S-(R*,R*))-isomer
- ubenimex
-
SMILESCC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O
-
InChIKeyVGGGPCQERPFHOB-UHFFFAOYSA-N
- Pubchem - Bestatin
- Wikipedia - bestatin
Ubenimex (INN), also known more commonly as bestatin, is a competitive, reversible protease inhibitor. It is an inhibitor of arginyl aminopeptidase (aminopeptidase B), leukotriene A4 hydrolase (a zinc metalloprotease that displays both epoxide hydrolase and aminopeptidase activities), alanyl aminopeptidase (aminopeptidase M/N), leucyl/cystinyl aminopeptidase (oxytocinase/vasopressinase), and membrane dipeptidase (leukotriene D4 hydrolase). It is being studied for use in the treatment of acute myelocytic leukemia and lymphedema.
Suppliers
Most-cited Publications
Areas of Application
Safety
Trends
Alternate Names
External Links
Synthesis
Similar Compounds
Bestatin (TN)
(58970-76-6)
10 alternate names
3 suppliers
PINDONE
(83-26-1)
10 alternate names
4 safety hazards
3 suppliers
Carbutamide
(339-43-5)
10 alternate names
3 suppliers
VALONE
(83-28-3)
10 alternate names
3 suppliers
LINALYL ANTHRANILATE
(7149-26-0)
10 alternate names
3 suppliers
Isopentyl cinnamate
(85180-66-1, 7779-65-9)
10 alternate names
3 suppliers
10094-34-5
(10094-34-5)
10 alternate names
3 suppliers
tert-Butyl peroxybenzoate
(614-45-9)
10 alternate names
2 safety hazards
3 suppliers
4-tert-Octylphenol
(140-66-9)
10 alternate names
6 safety hazards
3 suppliers
clofibric acid
(882-09-7)
10 alternate names
3 suppliers
Dihydrocapsaicin
(19408-84-5)
10 alternate names
3 suppliers
Iprobenfos
(26087-47-8)
10 alternate names
4 safety hazards
3 suppliers
tert-Butyl cumyl peroxide
(3457-61-2)
10 alternate names
4 safety hazards
3 suppliers
Isoamyl salicylate
(87-20-7)
10 alternate names
3 suppliers
2,4-D ISOOCTYL ESTER
(25168-26-7)
10 alternate names
3 suppliers
Imazapyr
(81334-34-1)
10 alternate names
1 safety hazard
3 suppliers
Sulfoxide
(120-62-7)
10 alternate names
3 suppliers
Triton X-100
(9002-93-1, 2315-67-5, 9063-89-2)
10 alternate names
2 safety hazards
3 suppliers
n-acetyl-a-aspartylglutamic acid
(3106-85-2)
10 alternate names
3 suppliers
4376-20-9
(4376-20-9)
10 alternate names
3 suppliers
ISOBUTYL ANTHRANILATE
(7779-77-3)
10 alternate names
3 suppliers
Isospaglumic acid
(3106-85-2)
10 alternate names
3 suppliers
Perindoprilat
(95153-31-4)
10 alternate names
3 suppliers
HEDTA
(150-39-0)
10 alternate names
3 suppliers
Dimethylbenzylcarbinyl acetate
(151-05-3)
10 alternate names
3 suppliers
Enterodiol
(80226-00-2)
10 alternate names
3 suppliers
Ciprofibrate
(52214-84-3)
10 alternate names
3 suppliers
Phenoxyethyl isobutyrate
(103-60-6)
10 alternate names
3 suppliers
NNK (carcinogen)
(64091-50-5, 64091-91-4)
10 alternate names
3 suppliers
Propranolol hydrochloride
(3506-09-0, 318-98-9)
10 alternate names
3 suppliers
chlorpropham
(101-21-3)
10 alternate names
2 safety hazards
3 suppliers
Dormatylan
(309-43-3)
10 alternate names
3 suppliers
Immenoctal
(309-43-3)
10 alternate names
3 suppliers
RACTOPAMINE
(97825-25-7)
10 alternate names
3 suppliers
Propyzamide
(23950-58-5)
10 alternate names
4 safety hazards
3 suppliers
Bifenazate
(149877-41-8)
10 alternate names
5 safety hazards
3 suppliers
2,4-D 2-Ethylhexyl ester
(1928-43-4)
10 alternate names
3 suppliers
Zoxamide
(156052-68-5)
10 alternate names
2 safety hazards
3 suppliers
DIBUTYL PHENYL PHOSPHATE
(2528-36-1)
10 alternate names
3 safety hazards
3 suppliers
ISOPHYTOL
(505-32-8)
10 alternate names
2 safety hazards
3 suppliers
Prilocaine hydrochloride
(1786-81-8)
10 alternate names
3 suppliers
Cinoxate
(104-28-9)
10 alternate names
3 suppliers
Bestatin
CAS Directory
