| Weight | 348.486 g/mol |
|---|---|
| Formula | C24H28O2 |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 3 |
Bexarotene (153559-49-0)
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#56 in Neurology
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#278 in Neuroscience
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#1276 in Biology
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#1476 in Chemistry
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- Bexarotene Is Effective and Safe for Treatment of Refractory Advanced-Stage Cutaneous T-Cell Lymphoma: Multinational Phase II-III Trial Results (Journal of Clinical Oncology, 2001)
- Phase 2 and 3 Clinical Trial of Oral Bexarotene (Targretin Capsules) for the Treatment of Refractory or Persistent Early-Stage Cutaneous T-Cell Lymphoma (Archives of Dermatology, 2001)
- Induction of Apoptosis by Bexarotene in Cutaneous T-Cell Lymphoma Cells Relevance to Mechanism of Therapeutic Action (Clinical Cancer Research, 2002)
- Optimizing bexarotene therapy for cutaneous T-cell lymphoma (Journal of The American Academy of Dermatology, 2002)
- Phase 1 and 2 Trial of Bexarotene Gel for Skin-Directed Treatment of Patients With Cutaneous T-Cell Lymphoma (Archives of Dermatology, 2002)
- Multi-Institutional Phase I/II Trial of Oral Bexarotene in Combination With Cisplatin and Vinorelbine in Previously Untreated Patients With Advanced NonSmall-Cell Lung Cancer (Journal of Clinical Oncology, 2001)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
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- Pubchem - Bexarotene
- Wikipedia - bexarotene
Bexarotene (brand name: Targretin) is an antineoplastic (anti-cancer) agent approved by the U.S.Food and Drug Administration (FDA) (in late 1999) and the European Medicines Agency (EMA) (early 2001) for use as a treatment for cutaneous T cell lymphoma (CTCL). It is a third-generation retinoid.
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Bexarotene
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