Weight | 523.973 g/mol |
---|---|
Formula | C28H27ClF5NO |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 1 |
Aromatic Rings | 3 |
Rotatable Bonds | 7 |
PENFLURIDOL (26864-56-2)
R-16341 · Semap · R16341
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- Sigma-Aldrich - PENFLURIDOL149.50 USD
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- TCI - PENFLURIDOL86.00 - 297.00 USD
- Safety of haloperidol and penfluridol in pregnancy: a multicenter, prospective, controlled study. (The Journal of Clinical Psychiatry, 2005)
- The Effect of Long-Term Penfluridol Treatment on the Sensitivity of the Dopamine Receptors in the Nucleus accumbens and in the Corpus striatum (Psychopharmacology, 1975)
- The pharmacology of penfluridol (R 16341) a new potent and orally long-acting neuroleptic drug (European Journal of Pharmacology, 1970)
- Reversal of mefloquine resistance with penfluridol in isolates of Plasmodium falciparum from south-west Nigeria (Transactions of The Royal Society of Tropical Medicine and Hygiene, 1993)
- Neuroleptic drugs attenuate calcium influx and tension development in rabbit thoracic aorta: effects of pimozide, penfluridol, chlorpromazine, and haloperidol (Proceedings of the National Academy of Sciences of the United States of America, 1985)
- LC-MS-MS analysis of the neuroleptics clozapine, flupentixol, haloperidol, penfluridol, thioridazine, and zuclopenthixol in hair obtained from psychiatric patients. (Journal of Analytical Toxicology, 2002)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - R-16341
- Semap
- R16341
- R 16341
- Janssen Brand of Penfluridol
-
SMILESC1CN(CCC1(C2=CC(=C(C=C2)Cl)C(F)(F)F)O)CCCC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F
-
InChIKeyMDLAAYDRRZXJIF-UHFFFAOYSA-N
- Pubchem - PENFLURIDOL
- Wikipedia - penfluridol
Penfluridol (Semap, Micefal, Longoperidol) is a highly potent, first generation diphenylbutylpiperidine antipsychotic. It was discovered at Janssen Pharmaceutica in 1968. Related to other diphenylbutylpiperidine antipsychotics, pimozide and fluspirilene, penfluridol has an extremely long elimination half-life and its effects last for many days after single oral dose.
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