| Weight | 538.128 g/mol |
|---|---|
| Formula | C32H40ClNO4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 10 |
FEXOFENADINE HYDROCHLORIDE (153439-40-8)
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- Double-blind, placebo-controlled study comparing the efficacy and safety of fexofenadine hydrochloride (120 and 180 mg once daily) and cetirizine in seasonal allergic rhinitis (The Journal of Allergy and Clinical Immunology, 1999)
- Comparison of the efficacy, safety and quality of life provided by fexofenadine hydrochloride 120 mg, loratadine 10 mg and placebo administered once daily for the treatment of seasonal allergic rhinitis (Clinical & Experimental Allergy, 2000)
- Efficacy and Safety of Fexofenadine Hydrochloride for Treatment of Seasonal Allergic Rhinitis (Annals of Allergy Asthma & Immunology, 1997)
- Pharmacokinetics, pharmacodynamics, and tolerance of single and multipledose fexofenadine hydrochloride in healthy male volunteers (Clinical Pharmacology & Therapeutics, 1998)
- Onset of Action, Efficacy, and Safety of a Single Dose of Fexofenadine Hydrochloride for Ragweed Allergy Using an Environmental Exposure Unit (Annals of Allergy Asthma & Immunology, 1997)
- Randomized, double-masked comparison of olopatadine ophthalmic solution, mometasone furoate monohydrate nasal spray, and fexofenadine hydrochloride tablets using the conjunctival and nasal allergen challenge models. (Clinical Therapeutics, 2003)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)(C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O)C(=O)O.Cl
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InChIKeyRRJFVPUCXDGFJB-UHFFFAOYSA-N
- Pubchem - FEXOFENADINE HYDROCHLORIDE
- Wikipedia - fexofenadine hydrochloride
Fexofenadine, sold under the trade name Allegra among others is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria. Therapeutically, fexofenadine is a selective peripheral H1-blocker. Fexofenadine is classified as a second-generation antihistamine because it is less able to pass the blood-brain barrier and cause sedation, compared to first-generation antihistamines.
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