Loperamide hydrochloride (34552-83-5)

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Suppliers

• 

  5 mg
  $45.00

  50 mg
  $75.00

  1 g
  $120.00

  10 g
  $150.00

  25 g
  $350.00

Consumer Products

• 

  Major Pharmaceuticals 006311 Loperamide Hydrochloride Anti-Diarrheal Tablet, Compare to Imodium A-D, Green, Boxed (Pack of 24)
  $7.96

  View ›

Most-cited Publications

• Delivery of Loperamide Across the Blood-Brain Barrier with Polysorbate 80-Coated Polybutylcyanoacrylate Nanoparticles (Pharmaceutical Research, 1997)
• Effects of loperamide on anal sphincter function in patients complaining of chronic diarrhea with fecal incontinence and urgency (Digestive Diseases and Sciences, 1982)
• Irinotecan (CPT-11) High-Dose Escalation Using Intensive High-Dose Loperamide to Control Diarrhea (Journal of the National Cancer Institute, 1994)
• Role of loperamide and placebo in management of irritable bowel syndrome (IBS) (Digestive Diseases and Sciences, 1984)
• Interaction of morphine, fentanyl, sufentanil, alfentanil, and loperamide with the efflux drug transporter P-glycoprotein. (Anesthesiology, 2002)
• Targeting the central nervous system: in vivo experiments with peptide-derivatized nanoparticles loaded with Loperamide and Rhodamine-123. (Journal of Controlled Release, 2007)

Areas of Application

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Trends

Alternate Names

• Loperamide
• Imodium
• Loperamide Monohydrochloride
• R 18553
• R-18553
• R18553
• SMILES
  CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4.Cl
• InChIKey
  PGYPOBZJRVSMDS-UHFFFAOYSA-N

External Links

• Pubchem - Loperamide hydrochloride
• Wikipedia - loperamide hydrochloride
  Loperamide, sold under the brand name Imodium among others, is a medication used to decrease the frequency of diarrhea. It is often used for this purpose in gastroenteritis, inflammatory bowel disease, and short bowel syndrome. It is not recommended for those with blood in the stool.

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Loperamide hydrochloride

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