| Weight | 499.651 g/mol |
|---|---|
| Formula | C32H37NO4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 11 |
Carebastine (90729-42-3)
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LabBot
- Characterization of Ebastine, Hydroxyebastine, and Carebastine Metabolism by Human Liver Microsomes and Expressed Cytochrome P450 Enzymes: Major Roles for CYP2J2 and CYP3A (Drug Metabolism and Disposition, 2006)
- Pharmacokinetics of the H1-receptor antagonist ebastine and its active metabolite carebastine in healthy subjects (Drug Research, 1994)
- Blood-brain barrier transport of H1-antagonist ebastine and its metabolite carebastine. (Journal of Drug Targeting, 2000)
- Simultaneous determination of the histamine H1-receptor antagonist ebastine and its two metabolites, carebastine and hydroxyebastine, in human plasma using high-performance liquid chromatography (Journal of Chromatography B: Biomedical Sciences and Applications, 2001)
- Microbial oxidation of terfenadine and ebastine into fexofenadine and carebastine. (Bioorganic & Medicinal Chemistry Letters, 2004)
- Cimetidine does not influence the metabolism of the H1-receptor antagonist ebastine to its active metabolite carebastine. (British Journal of Clinical Pharmacology, 1993)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)(C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)OC(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)O
-
InChIKeyXGHOVGYJHWQGCC-UHFFFAOYSA-N
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Carebastine
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