| Weight | 663.08 g/mol |
|---|---|
| Formula | C22H14Cl2I2N2O2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 4 |
Closantel (57808-65-8)
N-(5-chloro-4((4-chlorophenyl)cyanomethyl)-2-methylphenyl)-2-hydroxy-3,5-diiodobenzamide
Score:
#25 in Animal science
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#27 in Medicinal chemistry
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#42 in Zoology
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#4570 in Biology
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- Resistance of field strains of Haemonchus contortus to ivermectin, closantel, rafoxanide and the benzimidazoles in South Africa (Veterinary Record, 1988)
- Control of helminthosis in lambs by strategic treatment with closantel and broad-spectrum anthelmintics (Australian Veterinary Journal, 1986)
- Novel inhibitors of bacterial two-component systems with gram positive antibacterial activity : Pharmacophore identification based on the screening hit closantel (Bioorganic & Medicinal Chemistry Letters, 1998)
- The Metabolism and Fate of Closantel (Flukiver) in Sheep and Cattle (Drug Metabolism Reviews, 1987)
- THE EFFECT OF THE HYDROGEN IONOPHORE CLOSANTEL UPON THE PHARMACOLOGY AND ULTRASTRUCTURE OF THE ADULT LIVER FLUKE FASCIOLA-HEPATICA (Parasitology Research, 1990)
- Activity of closantel against adult triclabendazole-resistant Fasciola hepatica (Veterinary Record, 2000)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - N-(5-chloro-4((4-chlorophenyl)cyanomethyl)-2-methylphenyl)-2-hydroxy-3,5-diiodobenzamide
-
SMILESCC1=CC(=C(C=C1NC(=O)C2=CC(=CC(=C2O)I)I)Cl)C(C#N)C3=CC=C(C=C3)Cl
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InChIKeyJMPFSEBWVLAJKM-UHFFFAOYSA-N
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