| Weight | 414.777 g/mol |
|---|---|
| Formula | C17H17ClF6N2O |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 2 |
Mefloquine hydrochloride (51742-86-0, 51773-92-3)
Mefloquine · Lariam · Ro215998001
Score:
#435 in Microbiology
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#795 in Neuroscience
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#3482 in Biology
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#4357 in Chemistry
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- Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number. (The Lancet, 2004)
- Effects of artesunate-mefloquine combination on incidence of Plasmodium falciparum malaria and mefloquine resistance in western Thailand: a prospective study (The Lancet, 2000)
- Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine. (Proceedings of the National Academy of Sciences of the United States of America, 1994)
- pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum (Molecular Microbiology, 2005)
- Decreasing pfmdr1 Copy Number in Plasmodium falciparum Malaria Heightens Susceptibility to Mefloquine, Lumefantrine, Halofantrine, Quinine, and Artemisinin (The Journal of Infectious Diseases, 2006)
- Potent block of Cx36 and Cx50 gap junction channels by mefloquine (Proceedings of the National Academy of Sciences of the United States of America, 2004)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Mefloquine
- Lariam
- Ro215998001
- WR142,490
- Ro-21-5998-001
- WR 142,490
- Roche Brand of Mefloquine Hydrochloride
- Ro 21 5998 001
- Hoffmann La Roche Brand of Mefloquine Hydrochloride
- Hoffmann-La Roche Brand of Mefloquine Hydrochloride
- WR177,602
- WR-177,602
- Mephloquine
- WR 177,602
- WR-142,490
-
SMILESC1CCNC(C1)C(C2=CC(=NC3=C2C=CC=C3C(F)(F)F)C(F)(F)F)O.Cl
-
InChIKeyWESWYMRNZNDGBX-UHFFFAOYSA-N
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Mefloquine hydrochloride
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