| Weight | 288.435 g/mol |
|---|---|
| Formula | C18H28N2O |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 5 |
bupivacaine (2180-92-9, 38396-39-3)
Marcaine · Bupivacaine Hydrochloride · Sensorcaine
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#1114 in Chemistry
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- Cardiac Arrest Following Regional Anesthesia with Etidocaine or Bupivacaine (Anesthesiology, 1979)
- Central nervous and cardiovascular effects of i.v. infusions of ropivacaine, bupivacaine and placebo in volunteers. (BJA: British Journal of Anaesthesia, 1997)
- Acute Toxicity of Ropivacaine Compared with That of Bupivacaine (Anesthesia & Analgesia, 1989)
- Pretreatment or resuscitation with a lipid infusion shifts the dose-response to bupivacaine-induced asystole in rats. (Anesthesiology, 1998)
- Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed bupivacaine-related cardiac arrest. (Anesthesiology, 2006)
- Lipid Emulsion Infusion Rescues Dogs From Bupivacaine-Induced Cardiac Toxicity (Regional Anesthesia and Pain Medicine, 2003)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Marcaine
- Bupivacaine Hydrochloride
- Sensorcaine
- Marcain
- Carbostesin
- Bupivacain-RPR
- 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
- Bupivacaine Monohydrochloride, Monohydrate
- Bupivacaine Carbonate
- Svedocain Sin Vasoconstr
- Dolanaest
- Bupivacaine Anhydrous
- Bupivacain RPR
- Bupivacaina Braun
- Buvacaina
- Bupivacain Janapharm
-
SMILESCCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C
-
InChIKeyLEBVLXFERQHONN-UHFFFAOYSA-N
- Pubchem - bupivacaine
- Wikipedia - bupivacaine
Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease feeling in a specific area. It is used by injecting it into the area, around a nerve that supplies the area, or into the spinal canal's epidural space. It is available mixed with a small amount of epinephrine to make it last longer.
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Synthesis
Reactant
+
2,6-Dimethylaniline
(Schotten-Baumann amide from acid)
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4-[(3-chloro-2-methylphenyl)amino]-4-oxobutanoic acid
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2-cyano-N-(2-methylphenyl)acetamide
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3-[(2,4-dimethylphenyl)amino]-3-oxopropanoic acid
(58271-38-8)
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3-[(2-ethylbutanoyl)amino]-2-methylbenzoic acid
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N-(5-amino-2-methylphenyl)propanamide
(436089-02-0)
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893-36-7
(893-36-7)
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3-chloro-N-(2-methylphenyl)propanamide
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4-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione
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5-(2,3-dihydro-1H-indol-1-yl)-5-oxopentanoic acid
(239135-37-6)
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3-methyl-1-phenyl-2-piperazinone hydrochloride
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2-(butyrylamino)benzoic acid
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1-(4-amino-3,5-dimethylphenyl)-2-pyrrolidinone
(924830-53-5)
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2-amino-N-(2,3-dimethylphenyl)acetamide hydrochloride
(1049751-82-7)
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3-[(2-methylphenyl)amino]-3-oxopropanoic acid
(78987-20-9)
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N~1~-(2,5-dimethylphenyl)-beta-alaninamide hydrochloride
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N-(2,6-Dimethylphenyl)acetamide
(2198-53-0)
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AC1LECTA
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bupivacaine
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