Weight | 383.411 g/mol |
---|---|
Formula | C13H13N5O5S2 |
Hydrogen Acceptors | 9 |
Hydrogen Donors | 3 |
Aromatic Rings | 1 |
Rotatable Bonds | 5 |
ceftizoxime (68401-81-0)
Score:
#434 in Microbiology
,
#3465 in Biology
,
#4330 in Chemistry
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- Improved detection of methicillin-resistant Staphylococcus aureus using phenyl mannitol broth containing aztreonam and ceftizoxime (Journal of Clinical Microbiology, 2001)
- Antibacterial activity of ceftizoxime, a beta-lactamase-stable cephalosporin. (Antimicrobial Agents and Chemotherapy, 1980)
- Ceftizoxime (FK 749), a new parenteral cephalosporin: in vitro and in vivo antibacterial activities. (Antimicrobial Agents and Chemotherapy, 1979)
- Involvement of MRP4 (ABCC4) in the luminal efflux of ceftizoxime and cefazolin in the kidney (Molecular Pharmacology, 2007)
- COMMENT ; CEFTIZOXIME VERSUS VANCOMYCIN AND GENTAMICIN IN NEUROSURGICAL PROPHYLAXIS (Neurosurgery, 1993)
- Ciprofloxacin, azlocilin, ceftizoxime and amikacin alone and in combination against Gram-negative bacilli in an infected chamber model (Journal of Antimicrobial Chemotherapy, 1986)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=CCS3)C(=O)O
-
InChIKeyNNULBSISHYWZJU-UHFFFAOYSA-N
- Pubchem - ceftizoxime
- Wikipedia - ceftizoxime
Ceftizoxime is a third-generation cephalosporin available for parenteral administration. Unlike other third-generation cephalosporins, the whole C-3 side chain in ceftizoxime has been removed to prevent deactivation by hydrolytic enzymes. It rather resembles cefotaxime in its properties, but is not subject to metabolism.
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