Weight | 199.319 g/mol |
---|---|
Formula | C10H17NOS |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 0 |
Aromatic Rings | 0 |
Rotatable Bonds | 0 |
Cevimeline (107233-08-9)
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- A double-blind, randomized, placebo-controlled study of cevimeline in Sjgren's syndrome patients with xerostomia and keratoconjunctivitis sicca (Arthritis & Rheumatism, 2002)
- Cevimeline for the Treatment of Xerostomia in Patients With Sjgren Syndrome: A Randomized Trial (JAMA Internal Medicine, 2002)
- Therapeutic effect of cevimeline on dry eye in patients with Sjgren's syndrome: a randomized, double-blind clinical study (American Journal of Ophthalmology, 2004)
- Cevimeline for the Treatment of Postirradiation Xerostomia in Patients With Head and Neck Cancer (International Journal of Radiation Oncology Biology Physics, 2007)
- (+/-)-cis-2-methylspiro[1,3-oxathiolane-5,3'-quinuclidine] hydrochloride, hemihydrate (SNI-2011, cevimeline hydrochloride) induces saliva and tear secretions in rats and mice: the role of muscarinic acetylcholine receptors. (Japanese Journal of Pharmacology, 1998)
- The efficacy of cevimeline hydrochloride in the treatment of xerostomia in Sjgrens syndrome in southern Chinese patients: a randomised double-blind, placebo-controlled crossover study (Clinical Rheumatology, 2008)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1OC2(CN3CCC2CC3)CS1
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InChIKeyWUTYZMFRCNBCHQ-UHFFFAOYSA-N
- Pubchem - Cevimeline
- Wikipedia - cevimeline hydrochloride
Cevimeline (trade name Evoxac) is a parasympathomimetic and muscarinic agonist, with particular effect on M1 and M3 receptors. It is used in the treatment of dry mouth and especially associated with Sjgren's syndrome.
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