| Weight | 614.89 g/mol |
|---|---|
| Formula | C32H58N2O7S |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 12 |
CHAPS (75621-03-3)
Score:
#1860 in Physics
,
#2274 in Biochemistry
,
#4565 in Biology
,
#5785 in Chemistry
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LabBot
- The proteome of Mycoplasma genitalium. Chaps-soluble component. (FEBS Journal, 2000)
- Isotope-Edited Multidimensional NMR of Calcineurin-B in the Presence of the Non-Deuterated Detergent Chaps (Journal of Biomolecular NMR, 1993)
- Solubilization by CHAPS Detergent of BarbiturateEnhanced BenzodiazepineGABA Receptor Complex (Journal of Neurochemistry, 1982)
- Liposome Solubilization and Membrane Protein Reconstitution Using Chaps and Chapso (FEBS Journal, 1997)
- Arf1p, Chs5p and the ChAPs are required for export of specialized cargo from the Golgi (The EMBO Journal, 2006)
- Kinetics and Physical Parameters of Rat Brain Opioid Receptors Solubilized by Digitonin and CHAPS (Journal of Neurochemistry, 1986)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C
-
InChIKeyUMCMPZBLKLEWAF-UHFFFAOYSA-N
- Pubchem - CHAPS
- Wikipedia - 3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate
CHAPS is a zwitterionic surfactant used in the laboratory to solubilize biological macromolecules such as proteins. It may be synthesized from cholic acid and is zwitterionic due to its quaternary ammonium and sulfonate groups; it is structurally similar to certain bile acids, such as taurodeoxycholic acid and taurochenodeoxycholic acid. It is used as a non-denaturing solvent in the process of protein purification and is especially useful in purifying membrane proteins, which are often sparingly soluble or insoluble in aqueous solution due to their native hydrophobicity.
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