| Weight | 268.357 g/mol |
|---|---|
| Formula | C14H24N2O3 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
Ciclopirox olamine (41621-49-2)
ciclopirox · Loprox · Penlac
Score:
#516 in Microbiology
,
#4120 in Biology
,
#5191 in Chemistry
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- Cell cycle blockers mimosine, ciclopirox, and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support (The Journal of Neuroscience, 1996)
- Ciclopirox nail lacquer topical solution 8% in the treatment of toenail onychomycosis. (Journal of The American Academy of Dermatology, 2000)
- In vitro susceptibility testing of ciclopirox, terbinafine, ketoconazole and itraconazole against dermatophytes and nondermatophytes, and in vitro evaluation of combination antifungal activity (British Journal of Dermatology, 2003)
- Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells (Blood, 2009)
- The antifungal drug ciclopirox inhibits deoxyhypusine and proline hydroxylation, endothelial cell growth and angiogenesis in vitro. (International Journal of Cancer, 2002)
- Dermatopharmacology of ciclopirox nail lacquer topical solution 8% in the treatment of onychomycosis. (Journal of The American Academy of Dermatology, 2000)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - ciclopirox
- Loprox
- Penlac
- Dafnegin-CSC
- HOE-296
- ciclopiroxolamine
- cyclopirox
- 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone ethanolamine salt
- Batrafen
- HOE 296
- cyclopyroxolamine
-
SMILESCC1=CC(=O)N(C(=C1)C2CCCCC2)O.C(CO)N
-
InChIKeyMBRHNTMUYWQHMR-UHFFFAOYSA-N
- Pubchem - Ciclopirox olamine
- Wikipedia - ciclopirox olamine
Ciclopirox olamine is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. It is most useful against Tinea versicolor. It is sold under many brand names worldwide.
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Ciclopirox olamine
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