| Weight | 393.88 g/mol |
|---|---|
| Formula | C22H23ClF3N |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 6 |
Cinacalcet hydrochloride (364782-34-3)
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- Cinacalcet Hydrochloride Maintains Long-Term Normocalcemia in Patients with Primary Hyperparathyroidism (The Journal of Clinical Endocrinology and Metabolism, 2005)
- Cinacalcet hydrochloride reduces the serum calcium concentration in inoperable parathyroid carcinoma (The Journal of Clinical Endocrinology and Metabolism, 2007)
- Cinacalcet hydrochloride treatment significantly improves all-cause and cardiovascular survival in a large cohort of hemodialysis patients. (Kidney International, 2010)
- Cinacalcet Hydrochloride Is an Effective Treatment for Secondary Hyperparathyroidism in Patients With CKD Not Receiving Dialysis (American Journal of Kidney Diseases, 2005)
- Parathyroidectomy Versus Cinacalcet HydrochlorideBased Medical Therapy in the Management of Hyperparathyroidism in ESRD: A Cost Utility Analysis (American Journal of Kidney Diseases, 2007)
- Pharmacokinetics, pharmacodynamics, and safety of cinacalcet hydrochloride in hemodialysis patients at doses up to 200 mg once daily (American Journal of Kidney Diseases, 2004)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl
-
InChIKeyQANQWUQOEJZMLL-UHFFFAOYSA-N
- Pubchem - Cinacalcet hydrochloride
- Wikipedia - cinacalcet hydrochloride
Cinacalcet (INN) is a drug that acts as a calcimimetic (i.e. it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in various human organ tissues (Van Wagenen et al. (2001), U.S.
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Cinacalcet hydrochloride
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