| Weight | 326.831 g/mol |
|---|---|
| Formula | C18H19ClN4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 1 |
clozapine (5786-21-0)
Clozaril · Leponex
Score:
#110 in Neuroscience
,
#569 in Biology
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- Sigma-Aldrich - clozapine80.50 - 565.95 USD
- Fisher Scientific - Search for clozapine
- TCI - clozapine170.00 - 860.00 USD
- Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine. (Archives of General Psychiatry, 1988)
- Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. (Nature, 1991)
- Positron Emission Tomographic Analysis of Central D1 and D2 Dopamine Receptor Occupancy in Patients Treated With Classical Neuroleptics and Clozapine: Relation to Extrapyramidal Side Effects (Archives of General Psychiatry, 1992)
- The Effects of Clozapine, Risperidone, and Olanzapine on Cognitive Function in Schizophrenia (Schizophrenia Bulletin, 1999)
- Clozapine Treatment for Suicidality in Schizophrenia: International Suicide Prevention Trial (InterSePT) (Archives of General Psychiatry, 2003)
- Clozapine-induced agranulocytosis. Incidence and risk factors in the United States. (The New England Journal of Medicine, 1993)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Clozaril
- Leponex
-
SMILESCN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl
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InChIKeyZUXABONWMNSFBN-UHFFFAOYSA-N
- Pubchem - clozapine
- Wikipedia - clozapine
Clozapine, sold under the brand name Clozaril among others, is an atypical antipsychotic medication. It is mainly used for schizophrenia that does not improve following the use of other antipsychotic medications. In those with schizophrenia and schizoaffective disorder it may decrease the rate of suicidal behavior.
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clozapine
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