| Weight | 602.589 g/mol |
|---|---|
| Formula | C30H34O13 |
| Hydrogen Acceptors | 13 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 2 |
Cocculin (124-87-8)
Picrotoxin
Score:
#532 in Neuroscience
,
#2438 in Biology
,
#3035 in Chemistry
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- A study of the action of picrotoxin on the inhibitory neuromuscular junction of the crayfish. (The Journal of Physiology, 1969)
- Blockage of caudate-evoked inhibition of neurons in the substantia nigra by picrotoxin (Brain Research, 1971)
- Effects of picrotoxin and strychnine on rabbit retinal ganglion cells: lateral interactions for cells with more complex receptive fields. (The Journal of Physiology, 1978)
- Picrotoxin-induced epileptiform activity in hippocampus: role of endogenous versus synaptic factors (Journal of Neurophysiology, 1984)
- Effect of antipsychotic drugs on the firing of dorsal raphe cells. II. Reversal by picrotoxin (European Journal of Pharmacology, 1976)
- Effects of muscimol and picrotoxin on single unit activity of substantia nigra neurons (Brain Research, 1980)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Picrotoxin
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SMILESCC(=C)C1C2C3C4(C(C1C(=O)O2)(CC5C4(O5)C(=O)O3)O)C.CC12C3C4C(C(C1(CC5C2(O5)C(=O)O3)O)C(=O)O4)C(C)(C)O
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InChIKeyVJKUPQSHOVKBCO-UHFFFAOYSA-N
- Pubchem - Cocculin
- Wikipedia - picrotoxin
Picrotoxin, also known as cocculin, is a poisonous crystalline plant compound. It was first isolated by the French pharmacist and chemist Pierre Franois Guillaume Boullay (17771869) in 1812. The name "picrotoxin" is a combination of the Greek words "picros" (bitter) and "toxicon" (poison).
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