| Weight | 1202.635 g/mol |
|---|---|
| Formula | C62H111N11O12 |
| Hydrogen Acceptors | 12 |
| Hydrogen Donors | 5 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 15 |
Cyclosporine
Score:
#198 in Biochemistry
,
#800 in Biology
,
#880 in Chemistry
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- Cyclosporine in severe ulcerative colitis refractory to steroid therapy. (The New England Journal of Medicine, 1994)
- Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia (The New England Journal of Medicine, 1986)
- Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction (The New England Journal of Medicine, 2008)
- A comparison of tacrolimus (FK506) and cyclosporine for immunosuppression after cadaveric renal transplantation (Transplantation, 1997)
- Cyclosporine induces cancer progression by a cell-autonomous mechanism (Nature, 1999)
- Placebo-controlled study of mycophenolate mofetil combined with cyclosporine and corticosteroids for prevention of acute rejection (The Lancet, 1995)
- H302: Harmful if swallowed
Warning Acute toxicity, oral - Category 4 - H360: May damage fertility or the unborn child
Danger Reproductive toxicity - Category 1A, 1B - H370: Causes damage to organs
Danger Specific target organ toxicity, single exposure - Category 1 -
SMILESCCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
-
InChIKeyPMATZTZNYRCHOR-UHFFFAOYSA-N
- Pubchem - Cyclosporine
- Wikipedia - cyclosporine
Ciclosporin, also spelled cyclosporine and cyclosporin, is an immunosuppressant medication and natural product. It is used by mouth and injection into a vein for rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, and in organ transplants to prevent rejection. It is also used as eye drops for keratoconjunctivitis sicca (dry eyes).
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Alternate Names
Estimated Properties
| Density | 1.03 g/cm3 | EPA T.E.S.T. |
|---|---|---|
| Density | 1.03 g/cm3 | EPA T.E.S.T. |
| Flash Point | 780.49 C | EPA T.E.S.T. |
| Flash Point | 780.49 C | EPA T.E.S.T. |
| Water Solubility | 2.01 mg/L | EPA T.E.S.T. |
| Water Solubility | 2.01 mg/L | EPA T.E.S.T. |
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