Weight | 1301.578 g/mol |
---|---|
Formula | C56H100N16O17S |
Hydrogen Acceptors | 20 |
Hydrogen Donors | 20 |
Aromatic Rings | 1 |
Rotatable Bonds | 29 |
Aerosporin (1405-20-5)
Polymyxin B · Polymyxin B Sulfate
Score:
#191 in Microbiology
,
#707 in Biochemistry
,
#1972 in Biology
,
#2398 in Chemistry
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- Binding of polymyxin B to the lipid A portion of bacterial lipopolysaccharides. (Immunochemistry, 1976)
- Early Use of Polymyxin B Hemoperfusion in Abdominal Septic Shock: The EUPHAS Randomized Controlled Trial (JAMA, 2009)
- Polymyxin B Sulfate and Colistin: Old Antibiotics for Emerging Multiresistant Gram-Negative Bacteria (Annals of Pharmacotherapy, 1999)
- Polymyxin B for the treatment of multidrug-resistant pathogens: a critical review (Journal of Antimicrobial Chemotherapy, 2007)
- Clinical and molecular epidemiology of acinetobacter infections sensitive only to polymyxin B and sulbactam (The Lancet, 1994)
- Contemporary Assessment of Antimicrobial Susceptibility Testing Methods for Polymyxin B and Colistin: Review of Available Interpretative Criteria and Quality Control Guidelines (Journal of Clinical Microbiology, 2001)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Polymyxin B
- Polymyxin B Sulfate
-
SMILESCCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCN)CC2=CC=CC=C2)CC(C)C)CCN)CCN)C(C)O.OS(=O)(=O)O
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InChIKeyHFMDLUQUEXNBOP-UHFFFAOYSA-N
- Pubchem - Aerosporin
- Wikipedia - polymyxin B
Polymyxin B is an antibiotic primarily used for resistant Gram-negative infections. It is derived from the bacterium Bacillus polymyxa. Polymyxin B is composed of a number of related compounds (see "Mixture composition").
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