| Weight | 663.903 g/mol |
|---|---|
| Formula | C33H49N3O7S2 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 5 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 9 |
Nelfinavir mesylate (159989-65-8)
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- Viracept (Nelfinavir Mesylate, AG1343): A Potent, Orally Bioavailable Inhibitor of HIV-1 Protease (Journal of Medicinal Chemistry, 1997)
- A Preliminary Evaluation of Nelfinavir Mesylate, an Inhibitor of Human Immunodeficiency Virus (HIV)-1 Protease, to Treat HIV Infection (The Journal of Infectious Diseases, 1998)
- Characterization of the selectivity and mechanism of human cytochrome P450 inhibition by the human immunodeficiency virus-protease inhibitor nelfinavir mesylate (Drug Metabolism and Disposition, 1998)
- Treatment of Human Immunodeficiency Virus 1-Infected Infants and Children with the Protease Inhibitor Nelfinavir Mesylate (Clinical Infectious Diseases, 1999)
- Nelfinavir Mesylate: A Protease Inhibitor (Annals of Pharmacotherapy, 1999)
- The application of accelerator mass spectrometry to absolute bioavailability studies in humans: simultaneous administration of an intravenous microdose of 14C-nelfinavir mesylate solution and oral nelfinavir to healthy volunteers. (The Journal of Clinical Pharmacology, 2005)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=C(C=CC=C1O)C(=O)NC(CSC2=CC=CC=C2)C(CN3CC4CCCCC4CC3C(=O)NC(C)(C)C)O.CS(=O)(=O)O
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- Pubchem - Nelfinavir mesylate
- Wikipedia - nelfinavir mesylate
Nelfinavir (brand name Viracept) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV). Nelfinavir belongs to the class of drugs known as protease inhibitors (PIs) and like other PIs is almost always used in combination with other antiretroviral drugs. Nelfinavir mesylate (Viracept, formerly AG1343) is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor (Ki=2nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection.
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Nelfinavir mesylate
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