Weight | 284.352 g/mol |
---|---|
Formula | C15H24O5 |
Hydrogen Acceptors | 5 |
Hydrogen Donors | 1 |
Aromatic Rings | 0 |
Rotatable Bonds | 0 |
Dihydroartemisinin (81496-81-3, 71939-50-9)
Score:
#510 in Microbiology
,
#1896 in Biochemistry
,
#4060 in Biology
,
#5115 in Chemistry
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- Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells (Life Sciences, 2001)
- Antimalarial activity of new water-soluble dihydroartemisinin derivatives. (Journal of Medicinal Chemistry, 1987)
- Modified Fixed-Ratio Isobologram Method for Studying In Vitro Interactions between Atovaquone and Proguanil or Dihydroartemisinin against Drug-Resistant Strains of Plasmodium falciparum (Antimicrobial Agents and Chemotherapy, 2004)
- Dihydroartemisinin-piperaquine against multidrug-resistant Plasmodium falciparum malaria in Vietnam: randomised clinical trial (The Lancet, 2004)
- Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin (Cancer Letters, 1995)
- Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison (The Lancet, 2006)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)O)C
-
InChIKeyBJDCWCLMFKKGEE-UHFFFAOYSA-N
- Pubchem - Dihydroartemisinin
- Wikipedia - Dihydroartemisinin
Dihydroartemisinin (also known as dihydroqinghaosu, artenimol or DHA) is a drug used to treat malaria. Dihydroartemisinin is the active metabolite of all artemisinin compounds (artemisinin, artesunate, artemether, etc.) and is also available as a drug in itself. It is a semi-synthetic derivative of artemisinin and is widely used as an intermediate in the preparation of other artemisinin-derived antimalarial drugs.
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