| Weight | 396.531 g/mol |
|---|---|
| Formula | C24H32N2O3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
ENADOLINE (124378-77-4)
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- Enadoline, a selective kappa opioid agonist: comparison with butorphanol and hydromorphone in humans (Psychopharmacology, 2001)
- Enadoline and Butorphanol: Evaluation of -Agonists on Cocaine Pharmacodynamics and Cocaine Self-Administration in Humans (Journal of Pharmacology and Experimental Therapeutics, 2001)
- Analgesic efficacy of enadoline versus placebo or morphine in postsurgical pain. (Clinical Neuropharmacology, 1996)
- Analgesic efficacy of the -receptor agonist, enadoline, in dental surgery pain (Clinical Neuropharmacology, 1996)
- Enadoline, a selective -opioid receptor agonist shows potent antihyperalgesic and antiallodynic actions in a rat model of surgical pain (Pain, 1999)
- The adrenergic receptor agonist, clonidine, potentiates the anti-parkinsonian action of the selective -opioid receptor agonist, enadoline, in the monoamine-depleted rat (British Journal of Pharmacology, 1999)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCN(C1CCC2(CCCO2)CC1N3CCCC3)C(=O)CC4=C5C=COC5=CC=C4
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InChIKeyJMBYBVLCYODBJQ-UHFFFAOYSA-N
- Pubchem - ENADOLINE
- Wikipedia - enadoline
Enadoline is a drug which acts as a highly selective -opioid agonist. In human studies, it produced visual distortions and feelings of dissociation, reminiscent of the effects of salvinorin A. It was studied as a potential analgesic, but abandoned because of the dose-limiting effects of dysphoria, which could be expected from a -opioid agonist.
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