| Weight | 418.968 g/mol |
|---|---|
| Formula | C26H27ClN2O |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 7 |
LOFEPRAMINE (23047-25-8)
Lomont · Feprapax · Gamanil
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- Placebo-controlled trial of lithium augmentation of fluoxetine and lofepramine (British Journal of Psychiatry, 1995)
- A randomised controlled trial to compare the cost-effectiveness of tricyclic antidepressants, selective serotonin reuptake inhibitors and lofepramine. (Health Technology Assessment, 2005)
- Lofepramine a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness (Drugs, 1989)
- A randomised placebo controlled exploratory study of vitamin B-12, lofepramine, and L-phenylalanine (the Cari Loder regime) in the treatment of multiple sclerosis (Journal of Neurology, Neurosurgery, and Psychiatry, 2002)
- Recurrent hyponatremia associated with sertraline and lofepramine. (American Journal of Psychiatry, 1997)
- The Galway study of panic disorder I: Clomipramine and lofepramine in DSM III-R panic disorder: A placebo controlled trial (Journal of Affective Disorders, 1992)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Lomont
- Feprapax
- Gamanil
- Leo 640
- Rosemont Brand of Lofepramine Hydrochloride
- Lopramine
- Ashbourne Brand of Lofepramine Hydrochloride
- Deftan
- Lofepramine Hydrochloride
- Merck Brand of Lofepramine Hydrochloride
- Gamonil
-
SMILESCN(CCCN1C2=CC=CC=C2CCC3=CC=CC=C31)CC(=O)C4=CC=C(C=C4)Cl
-
InChIKeySAPNXPWPAUFAJU-UHFFFAOYSA-N
- Pubchem - LOFEPRAMINE
- Wikipedia - lofepramine
Lofepramine, sold under the brand names Gamanil, Lomont, and Tymelyt among others, is a tricyclic antidepressant (TCA) which is used to treat depression. The TCAs are so named as they share the common property of having three rings in their chemical structure. Like most TCAs lofepramine is believed to work in relieving depression by increasing concentrations of the neurotransmitters norepinephrine and serotonin in the synapse, by inhibiting their reuptake.
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LOFEPRAMINE
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