| Weight | 418.368 g/mol |
|---|---|
| Formula | C22H25Cl2N3O |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 3 |
AZELASTINE HYDROCHLORIDE (79307-93-0, 37932-96-0)
azelastine · Astelin · Optivar
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- Inhibition of calcium ionophore (A23187)-stimulated histamine release from rat peritoneal mast cells by azelastine: Implications for its mode of action (European Journal of Pharmacology, 1983)
- Topical azelastine reduces eosinophil activation and intercellular adhesion molecule-1 expression on nasal epithelial cells: An antiallergic activity (The Journal of Allergy and Clinical Immunology, 1996)
- Azelastine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential. (Drugs, 1989)
- A novel intranasal therapy of azelastine with fluticasone for the treatment of allergic rhinitis (The Journal of Allergy and Clinical Immunology, 2012)
- Suppression of TNF-alpha secretion by azelastine in a rat mast (RBL-2H3) cell line: evidence for differential regulation of TNF-alpha release, transcription, and degranulation. (Journal of Immunology, 1997)
- Efficacy of azelastine nasal spray in the treatment of vasomotor (perennial nonallergic) rhinitis (Annals of Allergy Asthma & Immunology, 2001)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - azelastine
- Astelin
- Optivar
- A-5610
- Corifina
- Vividrin akut Azelastin
- Sanfer brand of azelastine hydrochloride
- Optilast
- Muro brand of azelastine
- A 5610
- Orion brand of azelastine hydrochloride
- Afluon
- Rhinolast
- Allergodil
- 4-(p-chlorobenzyl)-2-(N-methylperhydroazepinyl-(4))-1-(2H)-phthalazinone
- 4-((4-chlorophenyl)methyl)-2- (hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)- phthalazinone HCl
- Loxin
- Mann brand of azelastine hydrochloride
- Dagra brand of azelastine hydrochloride
- ASTA Medica brand of azelastine hydrochloride
- Wallace brand of azelastine hydrochloride
- Bayer brand of azelastine hydrochloride
- Viatris brand of azelastine hydrochloride
- Azeptin
-
SMILESCN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl.Cl
-
InChIKeyYEJAJYAHJQIWNU-UHFFFAOYSA-N
- Pubchem - AZELASTINE HYDROCHLORIDE
- Wikipedia - azelastine hydrochloride
Azelastine is a potent, second-generation, selective, histamine antagonist (histamine-H1-receptor antagonist) used as a first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis). Azelastine has been formulated both as a nasal spray and as eye drops and are available worldwide under many brand names.
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AZELASTINE HYDROCHLORIDE
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