Weight | 506.478 g/mol |
---|---|
Formula | C25H33Cl2N5O2 |
Hydrogen Acceptors | 7 |
Hydrogen Donors | 0 |
Aromatic Rings | 3 |
Rotatable Bonds | 10 |
NEFAZODONE HYDROCHLORIDE (82752-99-6)
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- Sigma-Aldrich - NEFAZODONE HYDROCHLORIDE123.50 - 764.00 USD
- Fisher Scientific - Search for NEFAZODONE HYDROCHLORIDE
- TCI - Search for NEFAZODONE HYDROCHLORIDE
- Electrochemical characterisation of nefazodone hydrochloride and voltammetric determination of the drug in pharmaceuticals and human serum (Analytica Chimica Acta, 2002)
- EVALUATION OF SLEEP ARCHITECTURE AND CYCLIC ALTERNATING PATTERN RATES IN DEPRESSED INSOMNIAC PATIENTS TREATED WITH NEFAZODONE HYDROCHLORIDE (American Journal of Therapeutics, 1999)
- Crystalline nefazodone hydrochloride dihydrate and process for the preparation thereof (2000)
- Determination of Nefazodone Hydrochloride Tablets by HPLC (Chinese Journal of Pharmaceuticals, 2003)
- Synthesis of Nefazodone Hydrochloride (Chinese Journal of Pharmaceuticals, 2003)
- RP-HPLC determination of nefazodone hydrochloride tablets (Chinese Journal of Pharmaceutical Analysis, 2007)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCC1=NN(C(=O)N1CCOC2=CC=CC=C2)CCCN3CCN(CC3)C4=CC(=CC=C4)Cl.Cl
-
InChIKeyDYCKFEBIOUQECE-UHFFFAOYSA-N
- Pubchem - NEFAZODONE HYDROCHLORIDE
- Wikipedia - nefazodone hydrochloride
Nefazodone, sold formerly under the brand names Serzone, Dutonin, and Nefadar among others, is an atypical antidepressant which was first marketed by Bristol-Myers Squibb in 1994 but has since largely been discontinued. BMS withdrew it from the market by 2004 due to decreasing sales due to the rare incidence of severe liver damage and the onset of generic competition. The incidence of severe liver damage is approximately 1 in every 250,000 to 300,000 patient-years.
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