| Weight | 223.279 g/mol |
|---|---|
| Formula | C14H13N3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 1 |
FADROZOLE (102676-47-1)
Score:
#5023 in Biology
,
#6478 in Chemistry
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- Evaluation of the Aromatase Inhibitor Fadrozole in a Short-Term Reproduction Assay with the Fathead Minnow (Pimephales promelas) (Toxicological Sciences, 2002)
- Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease (Journal of Medicinal Chemistry, 1991)
- Fadrozole HCL (CGS-16949A) versus megestrol acetate treatment of postmenopausal patients with metastatic breast carcinoma: Results of two randomized double blind controlled multiinstitutional trials (Cancer, 1996)
- Fadrozole: a potent and specific inhibitor of aromatase in the zebra finch brain. (General and Comparative Endocrinology, 1994)
- First-line fadrozole HCI (CGS 16949A) versus tamoxifen in postmenopausal women with advanced breast cancer Prospective randomised trial of the Swiss Group for Clinical Cancer Research SAKK 20/88 (Annals of Oncology, 1996)
- Effects of Fadrozole (CGS 16949A) and Letrozole (CGS 20267) on the inhibition of aromatase activity in breast cancer patients (Breast Cancer Research and Treatment, 1994)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CC(N2C=NC=C2C1)C3=CC=C(C=C3)C#N
-
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- Pubchem - FADROZOLE
- Wikipedia - fadrozole
Fadrozole (INN), sold under the brand name Afema (by Novartis), is a selective, nonsteroidal aromatase inhibitor which is or has been used in Japan for the treatment of breast cancer.
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