| Weight | 383.165 g/mol |
|---|---|
| Formula | C10H21Cl2N2O7P |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 6 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 9 |
Glufosfamide (132682-98-5)
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- Phase I Trial of 6-Hour Infusion of Glufosfamide, a New Alkylating Agent With Potentially Enhanced Selectivity for Tumors That Overexpress Transmembrane Glucose Transporters: A Study of the European Organization for Research and Treatment of Cancer Early Clinical Studies Group (Journal of Clinical Oncology, 2000)
- A randomised Phase III trial of glufosfamide compared with best supportive care in metastatic pancreatic adenocarcinoma previously treated with gemcitabine (European Journal of Cancer, 2009)
- Glufosfamide administered using a 1-hour infusion given as first-line treatment for advanced pancreatic cancer. A phase II trial of the EORTC-new drug development group (European Journal of Cancer, 2003)
- Mechanistic aspects of the cytotoxic activity of glufosfamide, a new tumour therapeutic agent (British Journal of Cancer, 2000)
- European Organization for Research and Treatment of Cancer (EORTC) open label phase II study on glufosfamide administered as a 60-minute infusion every 3 weeks in recurrent glioblastoma multiforme (Annals of Oncology, 2003)
- Glufosfamide administered by 1-hour infusion as a second-line treatment for advanced non-small cell lung cancer: A phase II trial of the EORTC-New Drug Development Group (European Journal of Cancer, 2004)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC(CCl)NP(=O)(NCCCl)OC1C(C(C(C(O1)CO)O)O)O
-
InChIKeyPSVUJBVBCOISSP-UHFFFAOYSA-N
- Pubchem - Glufosfamide
- Wikipedia - glufosfamide
Glufosfamide, also known as glucophosphamide, D-glucose isophosphoramide mustard, D-19575 is an experimental cytotoxic chemotherapeutic agent for treatment of malignancies.
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