| Weight | 260.221 g/mol |
|---|---|
| Formula | C10H13FN2O5 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
Clevudine (163252-36-6)
Score:
#19 in Virology
,
#498 in Microbiology
,
#3953 in Biology
,
#4974 in Chemistry
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- A phase II dose-escalating trial of clevudine in patients with chronic hepatitis B (Hepatology, 2004)
- Twentyfourweek clevudine therapy showed potent and sustained antiviral activity in HBeAgpositive chronic hepatitis B (Hepatology, 2007)
- Antiviral activity of clevudine [L-FMAU, (1-(2-fluoro-5-methyl-, L-arabinofuranosyl) uracil)] against woodchuck hepatitis virus replication and gene expression in chronically infected woodchucks (Marmota monax) (Hepatology, 2001)
- Clevudine is highly efficacious in hepatitis B e antigen-negative chronic hepatitis B with durable off-therapy viral suppression. (Hepatology, 2007)
- Long-Term Therapy with Clevudine for Chronic Hepatitis B Can Be Associated with Myopathy Characterized by Depletion of Mitochondrial DNA (Hepatology, 2009)
- A 12week clevudine therapy showed potent and durable antiviral activity in HBeAgpositive chronic hepatitis B (Hepatology, 2006)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)F
-
InChIKeyGBBJCSTXCAQSSJ-UHFFFAOYSA-N
- Pubchem - Clevudine
- Wikipedia - clevudine
Clevudine (INN) is an antiviral drug for the treatment of hepatitis B (HBV). It is already approved for HBV in South Korea and the Philippines. It is marketed by Bukwang Pharmaceuticals in South Korea under the tradenames Levovir and Revovir.
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