| Weight | 299.661 g/mol |
|---|---|
| Formula | C9H12ClF2N3O4 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
GEMCITABINE HYDROCHLORIDE (122111-03-9, 12211-03-9)
gemcitabine · Gemzar · LY 188011
Score:
#443 in Biochemistry
,
#586 in Physics
,
#1457 in Biology
,
#1706 in Chemistry
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- Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. (Journal of Clinical Oncology, 1997)
- Erlotinib Plus Gemcitabine Compared With Gemcitabine Alone in Patients With Advanced Pancreatic Cancer: A Phase III Trial of the National Cancer Institute of Canada Clinical Trials Group (Journal of Clinical Oncology, 2005)
- FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer (The New England Journal of Medicine, 2011)
- Phase III Study Comparing Cisplatin Plus Gemcitabine With Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients With Advanced-Stage NonSmall-Cell Lung Cancer (Journal of Clinical Oncology, 2008)
- Gefitinib in Combination With Gemcitabine and Cisplatin in Advanced NonSmall-Cell Lung Cancer: A Phase III TrialINTACT 1 (Journal of Clinical Oncology, 2004)
- Adjuvant Chemotherapy With Gemcitabine vs Observation in Patients Undergoing Curative-Intent Resection of Pancreatic Cancer: A Randomized Controlled Trial (JAMA, 2007)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - gemcitabine
- Gemzar
- LY 188011
- gemcitabine, (beta-D-threo-pentafuranosyl)-isomer
- 2',2'-difluoro-2'-deoxycytidine
- 2',2'-DFDC
- LY-188011
- gemcitabine, (alpha-D-threo-pentofuranosyl)-isomer
- 2'-deoxy-2',2''-difluorocytidine-5'-O-monophosphate
- dFdCyd
- 2',2'-difluorodeoxycytidine
- gemcitabine, (D-threo-pentafuranosyl)-isomer
- 2'-deoxy-2'-difluorocytidine
-
SMILESC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.Cl
-
InChIKeyOKKDEIYWILRZIA-UHFFFAOYSA-N
- Pubchem - GEMCITABINE HYDROCHLORIDE
- Wikipedia - gemcitabine hydrochloride
Gemcitabine, sold under the brand name Gemzar, among others, is a chemotherapy medication used to treat a number of types of cancer. These cancers include breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer, and bladder cancer. It is given by slow injection into a vein.
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