| Weight | 198.314 g/mol |
|---|---|
| Formula | C10H22N4 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 3 |
GUANETHIDINE (645-43-2, 55-65-2)
Ismelin · Guanethidine Sulfate · Guanethidine Monosulfate
Score:
#529 in Neuroscience
,
#2432 in Biology
,
#3025 in Chemistry
"What do you need help with?"
LabBot
- Sigma-Aldrich - Search for GUANETHIDINE
- Fisher Scientific - Search for GUANETHIDINE
- TCI - Search for GUANETHIDINE
- A new method of destroying adrenergic nerves in adult animals using guanethidine (British Journal of Pharmacology, 1971)
- Guanethidine-sensitive release of neuropeptide Y-like immunoreactivity in the cat spleen by sympathetic nerve stimulation (Neuroscience Letters, 1984)
- INTRAVENOUS REGIONAL SYMPATHETIC BLOCK WITH GUANETHIDINE (The Lancet, 1974)
- Effects of chronic guanethidine treatment and adrenal medullectomy on plasma levels of catecholamines and corticosterone in forcibly immobilized rats. (Journal of Pharmacology and Experimental Therapeutics, 1979)
- INTERACTION OF GUANETHIDINE WITH ADRENERGIC NEURONS (Journal of Pharmacology and Experimental Therapeutics, 1965)
- Norepinephrine Depletion as a Possible Mechanism of Action of Guanethidine a New Hypotensive Agent (Experimental Biology and Medicine, 1960)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Ismelin
- Guanethidine Sulfate
- Guanethidine Monosulfate
- ((2-Hexahydro-1(2H)-azocinyl)ethyl)guanidine
- Octadine
- Isobarin
- Oktadin
- Guanethidine Sulfate (1:2)
- Guanethidine Sulfate (2:1)
- Guanethidine Sulfate (2:1), 14C-Labeled
- Guanethidine Sulfate (1:1)
-
SMILESC1CCCN(CCC1)CCN=C(N)N
-
InChIKeyACGDKVXYNVEAGU-UHFFFAOYSA-N
- Pubchem - GUANETHIDINE
- Wikipedia - guanethidine
Guanethidine is an antihypertensive drug that reduces the release of catecholamines, such as norepinephrine. Guanethidine is transported across the sympathetic nerve membrane by the same mechanism that transports norepinephrine itself (NET, uptake 1), and uptake is essential for the drug's action. Once guanethidine has entered the nerve, it is concentrated in transmitter vesicles, where it replaces norepinephrine.
Suppliers
Most-cited Publications
Areas of Application
Safety
Trends
Alternate Names
External Links
Synthesis
Similar Compounds
TRIBUTYLAMINE
(102-82-9, 6309-30-4)
12 alternate names
5 safety hazards
3 suppliers
Cyclohexyl isocyanate
(3173-53-3)
12 alternate names
3 suppliers
benzamidine
(618-39-3)
12 alternate names
3 suppliers
cyclohexane-1,2-diamine
(694-83-7)
12 alternate names
3 suppliers
1,4-Bis(3-aminopropyl)piperazine
(7209-38-3)
12 alternate names
3 suppliers
PENTAETHYLENEHEXAMINE
(4067-16-7)
12 alternate names
4 safety hazards
3 suppliers
1,8-Diamino-p-menthane
(80-52-4, 26183-13-1)
12 alternate names
3 suppliers
4-Guanidinobutyric acid
(463-00-3)
12 alternate names
3 suppliers
(1R,2R)-(-)-1,2-Diaminocyclohexane
(1121-22-8, 20439-47-8)
12 alternate names
3 suppliers
Phenethyl isocyanate
(1943-82-4)
12 alternate names
4 safety hazards
3 suppliers
7209-38-3
(7209-38-3)
12 alternate names
3 suppliers
CYCLOHEXANECARBOXYLIC ACID
(50825-29-1, 98-89-5)
12 alternate names
3 suppliers
2-Amino-5-diethylaminopentane
(140-80-7)
12 alternate names
3 suppliers
Cyclohexanone cyanohydrin
(931-97-5)
12 alternate names
3 suppliers
Dipentene
(7705-14-8, 9003-73-0, 8008-56-8, 65996-98-7, 8008-57-9, 138-86-3, 8028-38-4, 0008008-57-9)
12 alternate names
4 safety hazards
3 suppliers
D-Limonene
(5989-27-5, 68606-81-5, 5989-27-5, 65996-98-7)
12 alternate names
3 safety hazards
3 suppliers
1,6-Diisocyanatohexane
(822-06-0, 88357-62-4, 5124-30-1)
12 alternate names
7 safety hazards
3 suppliers
p-Phenylenediamine
(106-50-3)
12 alternate names
6 safety hazards
3 suppliers
1-Nitrosopiperidine
(100-75-4)
12 alternate names
1 safety hazard
3 suppliers
N-Nitrosodibutylamine
(924-16-3)
12 alternate names
1 safety hazard
3 suppliers
L-arginine
(74-79-3, 4455-52-1, 25212-18-4)
12 alternate names
3 suppliers
metformin
(1115-70-4, 657-24-9)
12 alternate names
3 suppliers
DICYCLOHEXYLAMINE
(101-83-7)
12 alternate names
8 safety hazards
3 suppliers
TETRAETHYLENEPENTAMINE
(27233-92-7, 112-57-2, 26913-06-4)
12 alternate names
6 safety hazards
3 suppliers
140-31-8
(28631-79-0, 140-31-8)
12 alternate names
7 safety hazards
3 suppliers
TRIALLYLAMINE
(102-70-5)
12 alternate names
3 safety hazards
3 suppliers
TRIPROPYLAMINE
(102-69-2)
12 alternate names
4 safety hazards
3 suppliers
Benzamide
(55-21-0)
12 alternate names
3 suppliers
3-(piperidin-2-yl)pyridine
(494-52-0, 13078-04-1)
12 alternate names
2 safety hazards
3 suppliers
Anabasine
(494-52-0, 13078-04-1)
12 alternate names
2 safety hazards
3 suppliers
N,N-Dimethyldodecylamine
(112-18-5, 68390-97-6, 68391-04-8)
12 alternate names
3 safety hazards
3 suppliers
2-(DIBUTYLAMINO)ETHANOL
(102-81-8)
12 alternate names
5 safety hazards
3 suppliers
(-)-Anabasine
(494-52-0)
12 alternate names
2 safety hazards
3 suppliers
piperidine-2-carboxylic acid
(535-75-1, 4043-87-2)
12 alternate names
3 suppliers
2-AMINOBENZAMIDE
(88-68-6)
12 alternate names
3 suppliers
Dibutylhexamethylenediamine
(4835-11-4)
12 alternate names
3 suppliers
Benzohydrazide
(613-94-5)
12 alternate names
3 suppliers
p-Menthane
(6069-98-3, 99-82-1, 1678-82-6)
12 alternate names
2 safety hazards
3 suppliers
(-)-Limonene
(5989-54-8)
12 alternate names
3 safety hazards
3 suppliers
Tributylphosphine
(998-40-3)
12 alternate names
1 safety hazard
3 suppliers
l-Pipecolic acid
(3105-95-1)
12 alternate names
3 suppliers
1-Phenylurea
(64-10-8)
12 alternate names
3 suppliers
Alloocimene
(7216-56-0, 673-84-7, 3016-19-1)
12 alternate names
3 suppliers
N,N-Dimethyltetradecylamine
(112-75-4)
12 alternate names
3 suppliers
p-MENTHAN-8-OL
(5114-00-1, 7322-63-6, 498-81-7, 29789-01-3)
12 alternate names
3 suppliers
L-histidinol
(4836-52-6)
12 alternate names
3 suppliers
2-Amino-1-phenylethanol
(4561-43-7, 7568-93-6)
12 alternate names
3 suppliers
benzyl isothiocyanate
(622-78-6)
12 alternate names
3 suppliers
3-Phenylpropanenitrile
(645-59-0)
12 alternate names
3 suppliers
(R)-Piperidine-2-carboxylic acid
(1723-00-8)
12 alternate names
3 suppliers
4771-80-6
(4771-80-6, 1338-24-5)
12 alternate names
3 suppliers
Isopulegol
(89-79-2, 50373-36-9)
12 alternate names
3 suppliers
D-Arginine
(157-06-2)
12 alternate names
3 suppliers
p-Menth-8-en-3-ol
(89-79-2, 7786-67-6)
12 alternate names
3 suppliers
Argininic acid
(157-07-3)
12 alternate names
3 suppliers
4-Hydroxycyclohexanecarboxylic acid
(17419-81-7, 3685-26-5)
12 alternate names
3 suppliers
Triamylamine
(621-77-2)
12 alternate names
3 suppliers
2-Amino-2-phenylacetic acid
(69-91-0, 2835-06-5)
12 alternate names
3 suppliers
4-aminophenol
(123-30-8)
12 alternate names
7 safety hazards
3 suppliers
1-Nitrosopyrrolidine
(35884-45-8, 930-55-2)
12 alternate names
1 safety hazard
3 suppliers
N-NITROSOPYRROLIDINE
(35884-45-8, 930-55-2)
12 alternate names
1 safety hazard
3 suppliers
cinnamaldehyde
(14371-10-9, 104-55-2, 57194-69-1)
12 alternate names
3 suppliers
CAS Directory
