| Weight | 129.167 g/mol |
|---|---|
| Formula | C4H11N5 |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 0 |
metformin (1115-70-4, 657-24-9)
Glucophage · Metformin Hydrochloride · Metformin HCl
Score:
#648 in Biochemistry
,
#1833 in Biology
,
#2192 in Chemistry
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- Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. (The New England Journal of Medicine, 2002)
- Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34) (The Lancet, 1998)
- Role of AMP-activated protein kinase in mechanism of metformin action (Journal of Clinical Investigation, 2001)
- Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. (The New England Journal of Medicine, 2006)
- Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus. Progressive requirement for multiple therapies (UKPDS 49) (JAMA, 1999)
- Effects of Exenatide (Exendin-4) on Glycemic Control and Weight Over 30 Weeks in Metformin-Treated Patients With Type 2 Diabetes (Diabetes Care, 2005)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Glucophage
- Metformin Hydrochloride
- Metformin HCl
- Dimethylguanylguanidine
- Dimethylbiguanidine
-
SMILESCN(C)C(=N)N=C(N)N
-
InChIKeyXZWYZXLIPXDOLR-UHFFFAOYSA-N
- Pubchem - metformin
- Wikipedia - metformin
Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. Limited evidence suggests metformin may prevent the cardiovascular disease and cancer complications of diabetes.
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