Weight | 125.131 g/mol |
---|---|
Formula | C5H7N3O |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 2 |
Aromatic Rings | 1 |
Rotatable Bonds | 0 |
5-Methylcytosine (554-01-8)
5 Methylcytosine · 5-Methylcytosine Monohydrochloride · 5 Methylcytosine Monohydrochloride
Score:
#1562 in Biochemistry
,
#3597 in Biology
,
#4513 in Chemistry
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- Sigma-Aldrich - Search for 5-Methylcytosine
- Fisher Scientific - Search for 5-Methylcytosine
- TCI - Search for 5-Methylcytosine
- Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1 (Science, 2009)
- A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. (Proceedings of the National Academy of Sciences of the United States of America, 1992)
- Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine (Science, 2011)
- Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain (Cell, 2011)
- LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition (Tetrahedron, 1998)
- Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2 (Nature, 2010)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 5 Methylcytosine
- 5-Methylcytosine Monohydrochloride
- 5 Methylcytosine Monohydrochloride
-
SMILESCC1=C(NC(=O)N=C1)N
-
InChIKeyLRSASMSXMSNRBT-UHFFFAOYSA-N
- Pubchem - 5-Methylcytosine
- Wikipedia - 5-methylcytosine
5-Methylcytosine is a methylated form of the DNA base cytosine that may be involved in the regulation of gene transcription. When cytosine is methylated, the DNA maintains the same sequence, but the expression of methylated genes can be altered (the study of this is part of the field of epigenetics). 5-Methylcytosine is incorporated in the nucleoside 5-methylcytidine.
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