| Weight | 128.131 g/mol |
|---|---|
| Formula | C5H8N2O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 0 |
Dihydrothymine (696-04-8)
5,6-dihydrothymine · 5,6-dihydrothymine, (S)-isomer · 5-methyldihydrouracil
Score:
#1582 in Physics
,
#1724 in Biochemistry
,
#4806 in Chemistry
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- 5-THYMINYL-5,6-DIHYDROTHYMINE FROM DNA IRRADIATED WITH ULTRAVIOLET LIGHT. (Biochemical and Biophysical Research Communications, 1970)
- Elevated urine, blood and cerebrospinal fluid levels of uracil and thymine in a child with dihydrothymine dehydrogenase deficiency (Clinica Chimica Acta, 1984)
- Excision of 5,6-dihydroxy-5,6-dihydrothymine, 5,6-dihydrothymine, and 5-hydroxycytosine from defined sequence oligonucleotides by Escherichia coli endonuclease III and Fpg proteins: kinetic and mechanistic aspects. (Biochemistry, 1999)
- Purification and properties of dihydrothymine dehydrogenase from rat liver. (Journal of Biological Chemistry, 1981)
- Processing of DNA base damage by DNA polymerases. Dihydrothymine and beta-ureidoisobutyric acid as models for instructive and noninstructive lesions. (Journal of Biological Chemistry, 1991)
- Spore Photoproduct (SP) Lyase from Bacillus subtilis Specifically Binds to and Cleaves SP (5-Thyminyl-5,6-Dihydrothymine) but Not Cyclobutane Pyrimidine Dimers in UV-Irradiated DNA (Journal of Bacteriology, 2000)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 5,6-dihydrothymine
- 5,6-dihydrothymine, (S)-isomer
- 5-methyldihydrouracil
-
SMILESCC1CNC(=O)NC1=O
-
InChIKeyNBAKTGXDIBVZOO-UHFFFAOYSA-N
- Pubchem - Dihydrothymine
- Wikipedia - dihydrothymine
Dihydrothymine is an intermediate in the metabolism of thymine.
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Synthesis
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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Dihydrothymine
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