| Weight | 103.081 g/mol |
|---|---|
| Formula | C2H5N3O2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 1 |
N-Methyl-N-nitrosourea
Methylnitrosourea · Nitrosomethylurea · NSC-23909
684-93-5, 68426-45-9, 28606-00-0
Score:
#190 in Biochemistry
,
#774 in Biology
,
#849 in Chemistry
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- Antitumor Actions of Keoxifene and Tamoxifen in the N-Nitrosomethylurea-induced Rat Mammary Carcinoma Model (Cancer Research, 1987)
- Nitrosamine-induced carcinogenesis. The alkylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate (Biochemical Journal, 1968)
- N-Nitrosomethylurea as Mammary Gland Carcinogen in Rats (Journal of the National Cancer Institute, 1975)
- Inhibition of 7,12-Dimethylbenz(a)anthracene- and N-Nitrosomethylurea-induced Rat Mammary Cancer by Dietary Flavonol Quercetin (Cancer Research, 1988)
- Prostate Carcinogenesis in N-methyl-N-nitrosourea (NMU)-Testosterone-Treated Rats Fed Tomato Powder, Lycopene, or Energy-Restricted Diets (Journal of the National Cancer Institute, 2004)
- Helicobacter pylori infection enhances N-methyl-N-nitrosourea-induced stomach carcinogenesis in the Mongolian gerbil. (Cancer Research, 1998)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H301: Toxic if swallowed
Danger Acute toxicity, oral - Category 3 - H340: May cause genetic defects
Danger Germ cell mutagenicity - Category 1A, 1B - H360: May damage fertility or the unborn child
Danger Reproductive toxicity - Category 1A, 1B - Methylnitrosourea
- Nitrosomethylurea
- NSC-23909
- NSC23909
- N Methyl N nitrosourea
- NSC 23909
-
SMILESCN(C(=O)N)N=O
-
InChIKeyZRKWMRDKSOPRRS-UHFFFAOYSA-N
- Pubchem - N-Methyl-N-nitrosourea
- Wikipedia - N-nitroso-N-methylurea
N-Nitroso-N-methylurea (NMU) is a highly reliable carcinogen, mutagen, and teratogen. NMU is an alkylating agent, and exhibits its toxicity by transferring its methyl group to nucleobases in nucleic acids, which can lead to AT:GC transition mutations. NMU is the traditional precursor in the synthesis of diazomethane.
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