N-NITROSODIMETHYLAMINE (62-75-9)

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Suppliers

• Sigma-Aldrich - N-NITROSODIMETHYLAMINE
  42.90 USD
• Fisher Scientific - Search for N-NITROSODIMETHYLAMINE
• TCI - Search for N-NITROSODIMETHYLAMINE

Most-cited Publications

• The Production of Malignant Primary Hepatic Tumours in the Rat by Feeding Dimethylnitrosamine (British Journal of Cancer, 1956)
• N-Nitrosodimethylamine (NDMA) as a Drinking Water Contaminant: A Review (Environmental Engineering Science, 2003)
• Formation of N-Nitrosodimethylamine (NDMA) from Dimethylamine during Chlorination (Environmental Science & Technology, 2002)
• Nitrosamine-induced carcinogenesis. The alkylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate (Biochemical Journal, 1968)
• Toxic liver injury and carcinogenesis. Methylation of rat-liver nucleic acids by dimethylnitrosamine in vivo. (Biochemical Journal, 1962)
• Induction of rat hepatic N-nitrosodimethylamine demethylase by acetone is due to protein stabilization. (Journal of Biological Chemistry, 1989)

Areas of Application

Safety

• Request a Demo
  Predict GHS Hazards for Any Chemical in silico.
  Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more.
• H227: Combustible liquid
  Warning Flammable liquids - Category 4
• H301: Toxic if swallowed
  Danger Acute toxicity, oral - Category 3
• H315: Causes skin irritation
  Warning Skin corrosion/irritation - Category 2
• H330: Fatal if inhaled
  Danger Acute toxicity, inhalation - Category 1, 2
• H350: May cause cancer
  Danger Carcinogenicity - Category 1A, 1B
• H370: Causes damage to organs
  Danger Specific target organ toxicity, single exposure - Category 1
• H411: Toxic to aquatic life with long lasting effects
  Hazardous to the aquatic environment, long-term hazard - Category 2

Trends

Alternate Names

• Dimethylnitrosamine
• Nitrosodimethylamine
• NDMA Nitrosodimethylamine
• N Nitrosodimethylamine
• SMILES
  CN(C)N=O
• InChIKey
  UMFJAHHVKNCGLG-UHFFFAOYSA-N

External Links

• Pubchem - N-NITROSODIMETHYLAMINE
• Wikipedia - N-nitrosodimethylamine
  N-Nitrosodimethylamine (NDMA), also known as dimethylnitrosamine (DMN), is a semi-volatile organic chemical, produced as by-product of several industrial processes and present at very low levels in certain foodstuffs, especially those cooked, smoked, or cured. NDMA is water-soluble, colorless, and its taste and odor are weak or absent. It is toxic to the liver and other organs, and is a suspected human carcinogen.

Synthesis

Methylboronic acid  +  Methylnitrosamine (Chan-Lam coupling reaction)

Synthesis of N-NITROSODIMETHYLAMINE ›

Similar Compounds

Ethylmethylnitrosamine (10595-95-6, 69278-54-2)

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1,1-DIMETHYLHYDRAZINE (30260-66-3, 57-14-7)

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trimethylamine (75-50-3)

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2-Methyl-1-propanol (78-83-1, 68989-27-5)

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ISOPROPYLAMINE (75-31-0)

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GLYCOLONITRILE (107-16-4)

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ETHYL NITRITE (109-95-5)

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1-Aminopropan-2-ol (2799-17-9, 78-96-6, 2799-16-8)

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Lactonitrile (78-97-7, 42492-95-5)

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3-METHYL-1-BUTENE (563-45-1)

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ISOBUTYL NITRITE (542-56-3)

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ISOPROPYL FORMATE (625-55-8)

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Butyl nitrite (544-16-1)

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Dimethylcyanamide (1467-79-4)

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Isopropyl isocyanate (1795-48-8)

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2-Methylbutyraldehyde (96-17-3)

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2-(Isopropylamino)ethanol (109-56-8)

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3-Hydroxypropanal (2134-29-4)

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acetaldehyde (75-07-0)

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ACROLEIN (25068-14-8, 107-02-8)

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ETHYLENE GLYCOL (9003-11-6, 107-21-1, 25322-68-3, 37225-26-6)

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ISOPRENE (78-79-5, 68441-58-7)

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DIETHANOLAMINE (61791-44-4, 61791-46-6, 111-42-2)

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1-Nitrosopyrrolidine (35884-45-8, 930-55-2)

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ethylenediamine (107-15-3, 27308-78-7)

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N-NITROSOPYRROLIDINE (35884-45-8, 930-55-2)

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Propionaldehyde (123-38-6)

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METHYL ISOTHIOCYANATE (556-61-6)

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butyraldehyde (123-72-8)

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GLYOXAL (107-22-2, 40094-65-3)

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1-Methoxy-2-propanol (107-98-2)

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2-chloroethanol (107-07-3)

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N-Nitrosodipropylamine (621-64-7)

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METHYL FORMATE (107-31-3)

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ISOBUTANE (75-28-5)

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ETHYL FORMATE (109-94-4)

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SEC-BUTYLAMINE (13952-84-6)

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ISOBUTYLAMINE (78-81-9)

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2-(Diethylamino)ethanol (100-37-8)

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Isobutyronitrile (78-82-0)

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N,N-DIMETHYLETHYLAMINE (598-56-1, 70955-13-4)

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2-(Methylamino)ethanol (109-83-1)

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ISOAMYL NITRITE (110-46-3)

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2-Propanethiol (75-33-2)

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Acetaldoxime (107-29-9, 5780-37-0)

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2-Bromopropane (75-26-3)

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ETHYL ISOCYANATE (109-90-0)

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N-METHYLDIETHANOLAMINE (105-59-9)

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(Z)-acetaldehyde oxime (107-29-9, 5775-72-4)

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Acetaldehyde, oxime (107-29-9, 5775-72-4, 5780-37-0)

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2-CHLOROPROPANE (75-29-6)

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3-Dimethylaminopropylamine (109-55-7)

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2-Methyl-1,3-propanediol (2163-42-0)

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N,N-Diethylhydroxylamine (3710-84-7)

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2-Isopropoxyethanol (109-59-1)

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Ethenone (463-51-4, 12071-23-7)

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2-METHYL-1-BUTANOL (137-32-6, 34713-94-5)

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2-Methylpentanal (123-15-9, 73513-30-1)

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3-(Methylthio)propionaldehyde (3268-49-3)

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Methyl nitrite (624-91-9)

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Methional (3268-49-3)

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1,2-DIAMINOPROPANE (78-90-0)

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PROPYL FORMATE (110-74-7)

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2-Ethylbutanal (97-96-1)

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Butyraldehyde oxime (5775-75-7, 110-69-0)

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Butanal oxime (5780-41-6, 110-69-0)

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N-NITROSODIMETHYLAMINE

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