| Weight | 117.108 g/mol |
|---|---|
| Formula | C3H7N3O2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 2 |
N-Ethyl-N-nitrosourea (759-73-9)
Ethylnitrosourea · Nitrosoethylurea · N Ethyl N nitrosourea
Score:
#197 in Neuroscience
,
#240 in Biochemistry
,
#925 in Biology
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#1022 in Chemistry
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- Specific-locus test shows ethylnitrosourea to be the most potent mutagen in the mouse. (Proceedings of the National Academy of Sciences of the United States of America, 1979)
- Persistence of O6-Ethylguanine in Rat-Brain DNA: Correlation with Nervous System-Specific Carcinogenesis by Ethylnitrosourea (Proceedings of the National Academy of Sciences of the United States of America, 1974)
- Comparison of imatinib mesylate, dasatinib (BMS-354825), and nilotinib (AMN107) in an N-ethyl-N-nitrosourea (ENU)based mutagenesis screen: high efficacy of drug combinations (Blood, 2006)
- Teratogenic and carcinogenic effects in the offspring after single injection of ethylnitrosourea to pregnant rats. (Nature, 1966)
- The N-Ethyl-N-Nitrosourea-Induced Goldenticket Mouse Mutant Reveals an Essential Function of Sting in the In Vivo Interferon Response to Listeria monocytogenes and Cyclic Dinucleotides (Infection and Immunity, 2011)
- Transplacental production with ethylnitrosourea of neoplasms of the nervous system in Sprague-Dawley rats. (American Journal of Pathology, 1971)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H301: Toxic if swallowed
Danger Acute toxicity, oral - Category 3 - H350: May cause cancer
Danger Carcinogenicity - Category 1A, 1B - Ethylnitrosourea
- Nitrosoethylurea
- N Ethyl N nitrosourea
-
SMILESCCN(C(=O)N)N=O
-
InChIKeyFUSGACRLAFQQRL-UHFFFAOYSA-N
- Pubchem - N-Ethyl-N-nitrosourea
- Wikipedia - N-ethyl-N-nitrosourea
ENU, also known as N-ethyl-N-nitrosourea (chemical formula C3H7N3O2), is a highly potent mutagen. For a given gene in mice, ENU can induce 1 new mutation in every 700 loci. It is also toxic at high doses.
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