Weight | 117.108 g/mol |
---|---|
Formula | C3H7N3O2 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 3 |
Aromatic Rings | 0 |
Rotatable Bonds | 2 |
glycocyamine (352-97-6)
guanidoacetic acid · guanidinoacetate · guanidinoacetic acid
Score:
#651 in Neuroscience
,
#1148 in Biochemistry
,
#2912 in Biology
,
#3647 in Chemistry
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- Sigma-Aldrich - glycocyamine38.20 - 97.20 USD
- Fisher Scientific - Search for glycocyamine
- TCI - glycocyamine40.00 - 337.00 USD
- Creatine replacement therapy in guanidinoacetate methyltransferase deficiency, a novel inborn error of metabolism (The Lancet, 1996)
- Guanidinoacetate methyltransferase deficiency: the first inborn error of creatine metabolism in man. (American Journal of Human Genetics, 1996)
- Creatine deficiency syndrome caused by guanidinoacetate methyltransferase deficiency: Diagnostic tools for a new inborn error of metabolism (The Journal of Pediatrics, 1997)
- Evolution of Phosphagen Kinase: Primary Structure of Glycocyamine Kinase and Arginine Kinase from Invertebrates (Journal of Molecular Biology, 1994)
- Improving treatment of guanidinoacetate methyltransferase deficiency: reduction of guanidinoacetic acid in body fluids by arginine restriction and ornithine supplementation. (Molecular Genetics and Metabolism, 2001)
- Severely altered guanidino compound levels, disturbed body weight homeostasis and impaired fertility in a mouse model of guanidinoacetate N-methyltransferase (GAMT) deficiency (Human Molecular Genetics, 2004)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - guanidoacetic acid
- guanidinoacetate
- guanidinoacetic acid
- glycocyamine, ion (1-)
- N-amidinoglycine
- glycocyamine, 2-(14)C-labeled
- glycocyamine monohydrochloride
-
SMILESC(C(=O)O)N=C(N)N
-
InChIKeyBPMFZUMJYQTVII-UHFFFAOYSA-N
- Pubchem - glycocyamine
- Wikipedia - glycocyamine
Glycocyamine (or guanidinoacetate) is a metabolite of glycine in which the amino group has been converted into a guanidine. Glycocyamine is a direct precursor of creatine and is used as a supplement. However the metabolism of creatine from glycocyamine in the liver causes a depletion of methyl groups.
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Synthesis
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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