| Weight | 536.797 g/mol |
|---|---|
| Formula | C35H52O4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 11 |
hyperforin (11079-53-1)
Score:
#468 in Neuroscience
,
#804 in Biochemistry
,
#2178 in Biology
,
#2681 in Chemistry
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- HYPERFORIN AS A POSSIBLE ANTIDEPRESSANT COMPONENT OF HYPERICUM EXTRACTS (Life Sciences, 1998)
- St. John's wort in mild to moderate depression: the relevance of hyperforin for the clinical efficacy. (Pharmacopsychiatry, 1998)
- 2.1 A crystal structure of human PXR in complex with the St. John's wort compound hyperforin. (Biochemistry, 2003)
- Hyperforin Represents the Neurotransmitter Reuptake Inhibiting Constituent of Hypericum Extract (Pharmacopsychiatry, 1998)
- Hyperforin, a Major Antidepressant Constituent of St. Johns Wort, Inhibits Serotonin Uptake by Elevating Free Intracellular Na+1 1 (Journal of Pharmacology and Experimental Therapeutics, 1999)
- Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis (Oncogene, 2002)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)C(=O)C12C(=O)C(=C(C(C1=O)(CC(C2(C)CCC=C(C)C)CC=C(C)C)CC=C(C)C)O)CC=C(C)C
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InChIKeyKGSZHKRKHXOAMG-UHFFFAOYSA-N
- Pubchem - hyperforin
- Wikipedia - Hyperforin
Hyperforin is a phytochemical produced by some of the members of the plant genus Hypericum, notably Hypericum perforatum (St John's wort). Hyperforin (along with adhyperforin) is believed to be one of the three chief active constituents of St. John's wort -the other two being hypericin (along with pseudohypericin) and several flavonoid constituents.
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