Weight | 270.284 g/mol |
---|---|
Formula | C16H14O4 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 0 |
Aromatic Rings | 3 |
Rotatable Bonds | 3 |
IMPERATORIN (482-44-0)
5-hydroxy-8-(1,1-dimethylallyl)psoralen · 8-isoamylenoxypsoralen
Score:
#1190 in Biochemistry
,
#3007 in Biology
,
#3757 in Chemistry
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- Anticonvulsant and acute neurotoxic effects of imperatorin, osthole and valproate in the maximal electroshock seizure and chimney tests in mice: A comparative study (Epilepsy Research, 2009)
- Imperatorin Inhibits HIV-1 Replication through an Sp1-dependent Pathway (Journal of Biological Chemistry, 2004)
- Preparative isolation of imperatorin, oxypeucedanin and isoimperatorin from traditional Chinese herb bai zhi Angelica dahurica (Fisch. ex Hoffm) Benth. et Hook using multidimensional high-speed counter-current chromatography (Journal of Chromatography A, 2006)
- Imperatorin induces vasodilatation possibly via inhibiting voltage dependent calcium channel and receptor-mediated Ca2+ influx and release. (European Journal of Pharmacology, 2007)
- Anticancer effects of imperatorin isolated from Angelica dahurica: induction of apoptosis in HepG2 cells through both death-receptor- and mitochondria-mediated pathways. (Chemotherapy, 2011)
- Imperatorin, a furanocoumarin from Angelica dahurica (Umbelliferae), induces cytochrome c-dependent apoptosis in human promyelocytic leukaemia, HL-60 Cells. (Pharmacology & Toxicology, 2002)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 5-hydroxy-8-(1,1-dimethylallyl)psoralen
- 8-isoamylenoxypsoralen
-
SMILESCC(=CCOC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2)C
-
InChIKeyOLOOJGVNMBJLLR-UHFFFAOYSA-N
- Pubchem - IMPERATORIN
- Wikipedia - pentosalen
Imperatorin is a furocoumarin and a phytochemical that has been isolated from Urena lobata L. (Malvaceae), Angelica archangelica, Angelica dahurica, Glehnia littoralis, Saposhnikovia divaricata, Cnidium monnieri, Incarvillea younghusbandii, and Zanthoxylum americanum mill. It is biosynthesized from umbelliferone, a coumarin derivative.
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