| Weight | 158.156 g/mol |
|---|---|
| Formula | C10H6O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 0 |
1,2-NAPHTHOQUINONE (524-42-5)
ortho-naphthoquinone · o-naphthoquinone
Score:
#721 in Biochemistry
,
#2439 in Chemistry
"What do you need help with?"
LabBot
- The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells. (Journal of Biological Chemistry, 1982)
- Site of action of the antimalarial hydroxynaphthoquinone, 2-[trans-4-(4'-chlorophenyl) cyclohexyl]-3- hydroxy-1,4-naphthoquinone (566C80) (Biochemical Pharmacology, 1992)
- Formation and reduction of glutathione-protein mixed disulfides during oxidative stress: A study with isolated hepatocytes and menadione (2-methyl-1,4-naphthoquinone) (Biochemical Pharmacology, 1987)
- Plumbagin (5-Hydroxy-2-methyl-1,4-naphthoquinone) Suppresses NF-B Activation and NF-B-regulated Gene Products Through Modulation of p65 and IB Kinase Activation, Leading to Potentiation of Apoptosis Induced by Cytokine and Chemotherapeutic Agents (Journal of Biological Chemistry, 2006)
- 2-and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: Synthesis and correlation between redox cycling activities and in vitro cytotoxicity (Journal of Medicinal Chemistry, 2001)
- Plumbagin (5-Hydroxy-2-methyl-1,4-naphthoquinone) Induces Apoptosis and Cell Cycle Arrest in A549 Cells through p53 Accumulation via c-Jun NH2-Terminal Kinase-Mediated Phosphorylation at Serine 15 in Vitro and in Vivo (Journal of Pharmacology and Experimental Therapeutics, 2006)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - ortho-naphthoquinone
- o-naphthoquinone
-
SMILESC1=CC=C2C(=C1)C=CC(=O)C2=O
-
InChIKeyKETQAJRQOHHATG-UHFFFAOYSA-N
- Pubchem - 1,2-NAPHTHOQUINONE
- Wikipedia - 1,2-naphthoquinone
1,2-Naphthoquinone or ortho-naphthoquinone is a polycyclic aromatic organic compound with formula C 10H 6O 2. This double ketone (quinone) is a reactive metabolite of naphthalene and is found in diesel exhaust particles. The accumulation of this toxic metabolite in rats from doses of naphthalene has been shown to cause eye damage, including the formation of cataracts.
Suppliers
Most-cited Publications
Areas of Application
Safety
Trends
Alternate Names
External Links
Synthesis
Similar Compounds
6-bromonaphthalene-1,2-dione
(6954-48-9)
3 alternate names
3 suppliers
4-chloronaphthalene-1,2-dione
(6655-90-9)
3 alternate names
3 suppliers
521-24-4
(521-24-4)
3 alternate names
3 suppliers
16214-27-0
(16214-27-0)
3 alternate names
3 suppliers
2-Benzylidene-1-tetralone
(6261-32-1)
3 alternate names
3 suppliers
2'-Methylpropiophenone
(2040-14-4)
3 alternate names
3 suppliers
2-benzylidene-1h-indene-1,3(2h)-dione
(5381-33-9)
3 alternate names
3 suppliers
2'-Methylbutyrophenone
(35028-06-9)
3 alternate names
3 suppliers
2-methyl-1-(2-methylphenyl)propan-1-one
(2040-21-3)
3 alternate names
3 suppliers
1-(2,4-dimethylphenyl)propan-1-one
(35031-55-1)
3 alternate names
3 suppliers
7396-99-8
(7396-99-8)
3 alternate names
3 suppliers
1-(2,5-dimethylphenyl)propan-1-one
(35031-52-8)
3 alternate names
3 suppliers
2040-15-5
(2040-15-5)
3 alternate names
3 suppliers
1H-Indene-1,3(2H)-dione, 2-[(4-fluorophenyl)methylene]-
(16210-64-3)
3 alternate names
3 suppliers
7-Methyl-1-indanone
(39627-61-7)
3 alternate names
3 suppliers
1-Benzosuberone
(826-73-3)
3 alternate names
3 suppliers
1-PHENYL-1,2-PROPANEDIONE
(579-07-7)
3 alternate names
3 suppliers
Propiophenone, 2,2',4',6'-tetramethyl-
(2040-22-4)
3 alternate names
3 suppliers
1-(2,4,6-trimethylphenyl)butan-1-one
(29786-97-8)
3 alternate names
3 suppliers
6,7-Dihydro-5H-benzocycloheptene
(7125-62-4)
3 alternate names
3 suppliers
35276-81-4
(35276-81-4)
3 alternate names
3 suppliers
2,4,6-Trimethylphenyl isobutyl ketone
(5344-18-3)
3 alternate names
3 suppliers
844-51-9
(844-51-9)
3 alternate names
3 suppliers
alpha-Tetralone
(29059-07-2, 529-34-0)
3 alternate names
3 suppliers
(2Z)-2-benzylidene-1,3-dioxoindane-5-carboxylic acid
(40462-12-2)
3 alternate names
3 suppliers
71172-79-7
(71172-79-7)
3 alternate names
3 suppliers
2-methyl-3-(2-oxo-2-phenylethyl)naphthoquinone
(88007-98-1)
3 alternate names
3 suppliers
2,4-DIMETHYLBENZOYLACETONITRILE
(53882-91-0)
3 alternate names
3 suppliers
2-Propionylbenzoic acid
(2360-45-4)
3 alternate names
3 suppliers
4-(2-Methylphenyl)-4-oxobutyric acid
(6939-36-2)
3 alternate names
3 suppliers
1-Indanone
(83-33-0, 30286-23-8)
3 alternate names
3 suppliers
3262-03-1
(3262-03-1)
3 alternate names
3 suppliers
Phenyl-p-benzoquinone
(363-03-1)
3 alternate names
3 suppliers
71172-44-6
(71172-44-6)
3 alternate names
3 suppliers
1-mesitylbutane-1,3-dione
(6450-57-3)
3 alternate names
3 suppliers
5-(2,3,5,6-TETRAMETHYLPHENYL)-5-OXOVALERIC ACID
(719295-43-9)
3 alternate names
3 suppliers
500892-07-9
(500892-07-9)
3 alternate names
3 suppliers
methyl 4-(2-methylphenyl)-4-oxobutanoate
(85616-39-3)
3 alternate names
3 suppliers
Cyclohexyl o-tolyl ketone
(2936-55-2)
3 alternate names
3 suppliers
4-(2,4-Dimethylphenyl)-4-oxobutanoic acid
(15880-03-2)
3 alternate names
3 suppliers
7-Methyl-1-tetralone
(22009-37-6)
3 alternate names
3 suppliers
7-Hydroxy-1-tetralone
(22009-38-7)
3 alternate names
3 suppliers
6500-65-8
(6500-65-8)
3 alternate names
3 suppliers
4-(2,5-Dimethylphenyl)-4-oxobutanoic acid
(5394-59-2)
3 alternate names
3 suppliers
5,6-Dimethyl-2,3-dihydro-1H-inden-1-one
(16440-97-4)
3 alternate names
3 suppliers
3331-46-2
(3331-46-2)
3 alternate names
3 suppliers
5-Hydroxy-1-indanone
(3470-49-3)
3 alternate names
3 suppliers
15880-01-0
(15880-01-0)
3 alternate names
3 suppliers
1,3-Indanedione
(606-23-5)
3 alternate names
3 suppliers
67405-48-5
(67405-48-5)
3 alternate names
3 suppliers
6-Methoxy-1-tetralone
(1078-19-9)
3 alternate names
3 suppliers
4-(2,3,5,6-TETRAMETHYLPHENYL)-4-OXOBUTYRIC ACID
(134948-69-9)
3 alternate names
3 suppliers
CYCLOHEXYL 2,4-DIMETHYLPHENYL KETONE
(2760-64-7)
3 alternate names
3 suppliers
2'-(Trifluoromethyl)propiophenone
(16185-96-9)
3 alternate names
3 suppliers
1,4-NAPHTHOQUINONE
(130-15-4)
3 alternate names
3 safety hazards
3 suppliers
7-Methoxy-1-tetralone
(6836-19-7)
3 alternate names
3 suppliers
2,3-Dihydro-1H-phenanthren-4-one
(778-48-3)
3 alternate names
3 suppliers
Plumbagin
(481-42-5)
3 alternate names
3 suppliers
2-Acetyl-1,3-indanedione
(1133-72-8)
3 alternate names
3 suppliers
25724-79-2
(25724-79-2)
3 alternate names
3 suppliers
5-Methoxy-1-indanone
(5111-70-6)
3 alternate names
3 suppliers
23342-32-7
(23342-32-7)
3 alternate names
3 suppliers
5-Chloro-1-indanone
(42348-86-7)
3 alternate names
3 suppliers
6072-57-7
(6072-57-7)
3 alternate names
3 suppliers
152605-34-0
(152605-34-0)
3 alternate names
3 suppliers
6342-87-6
(6342-87-6)
3 alternate names
3 suppliers
7-Chloro-1-tetralone
(26673-32-5)
3 alternate names
3 suppliers
6-Methoxy-1-indanone
(13623-25-1)
3 alternate names
3 suppliers
5-Fluoro-1-indanone
(700-84-5)
3 alternate names
3 suppliers
6-Fluoro-1-indanone
(1481-32-9)
3 alternate names
3 suppliers
2-Bromo-1-indanone
(1775-27-5)
3 alternate names
3 suppliers
1H-Indene-2-carboxylic acid
(41712-14-5)
3 alternate names
3 suppliers
6-Amino-1,2,3,4-tetrahydronaphthalen-1-one
(3470-53-9)
3 alternate names
3 suppliers
2-(2-methylphenyl)-1H-indene-1,3(2H)-dione
(60338-36-5)
3 alternate names
3 suppliers
7-Bromo-1-tetralone
(32281-97-3)
3 alternate names
3 suppliers
1-(4-nitrophenyl)propane-1,2-dione
(6159-25-7)
3 alternate names
3 suppliers
PINDONE
(83-26-1)
3 alternate names
4 safety hazards
3 suppliers
1,4-Anthraquinone
(635-12-1)
3 alternate names
3 suppliers
22009-40-1
(22009-40-1)
3 alternate names
3 suppliers
6-methoxy-7-methyl-3,4-dihydro-1(2H)-naphthalenone
(61495-10-1)
3 alternate names
3 suppliers
4-hydroxy-3,4-dihydronaphthalen-1(2H)-one
(21032-12-2)
3 alternate names
3 suppliers
6-Bromo-1-indanone
(14548-39-1)
3 alternate names
3 suppliers
28752-91-2
(28752-91-2)
3 alternate names
3 suppliers
175136-85-3
(175136-85-3)
3 alternate names
3 suppliers
1,4-Chrysenequinone
(100900-16-1)
3 alternate names
3 suppliers
5-Hydroxy-1-tetralone
(28315-93-7)
3 alternate names
3 suppliers
7319-63-3
(7319-63-3)
3 alternate names
3 suppliers
5-Bromo-1-indanone
(34598-49-7)
3 alternate names
3 suppliers
2979-69-3
(2979-69-3)
3 alternate names
3 suppliers
5-Aminoindan-1-one
(3470-54-0)
3 alternate names
3 suppliers
5,6-Dimethoxy-1-indanone
(2107-69-9)
3 alternate names
3 suppliers
3-Hydroxy-1-indanone
(26976-59-0)
3 alternate names
3 suppliers
tpi-1
(79756-69-7)
3 alternate names
3 suppliers
2-METHYL-1H-INDENE
(2177-47-1)
3 alternate names
3 suppliers
69975-65-1
(69975-65-1)
3 alternate names
3 suppliers
3-Methylindene-2-carboxylic acid
(34225-81-5)
3 alternate names
3 suppliers
2-(carboxycarbonyl)benzoic acid
(528-46-1)
3 alternate names
3 suppliers
2-(4-methylphenyl)-1H-indene-1,3(2H)-dione
(7561-48-0)
3 alternate names
3 suppliers
1,2-NAPHTHOQUINONE
CAS Directory
