Weight | 158.156 g/mol |
---|---|
Formula | C10H6O2 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 0 |
Aromatic Rings | 1 |
Rotatable Bonds | 0 |
1,4-NAPHTHOQUINONE (130-15-4)
Succivil
Score:
#1218 in Chemistry
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- The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells. (Journal of Biological Chemistry, 1982)
- Site of action of the antimalarial hydroxynaphthoquinone, 2-[trans-4-(4'-chlorophenyl) cyclohexyl]-3- hydroxy-1,4-naphthoquinone (566C80) (Biochemical Pharmacology, 1992)
- Formation and reduction of glutathione-protein mixed disulfides during oxidative stress: A study with isolated hepatocytes and menadione (2-methyl-1,4-naphthoquinone) (Biochemical Pharmacology, 1987)
- Plumbagin (5-Hydroxy-2-methyl-1,4-naphthoquinone) Suppresses NF-B Activation and NF-B-regulated Gene Products Through Modulation of p65 and IB Kinase Activation, Leading to Potentiation of Apoptosis Induced by Cytokine and Chemotherapeutic Agents (Journal of Biological Chemistry, 2006)
- 2-and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: Synthesis and correlation between redox cycling activities and in vitro cytotoxicity (Journal of Medicinal Chemistry, 2001)
- Plumbagin (5-Hydroxy-2-methyl-1,4-naphthoquinone) Induces Apoptosis and Cell Cycle Arrest in A549 Cells through p53 Accumulation via c-Jun NH2-Terminal Kinase-Mediated Phosphorylation at Serine 15 in Vitro and in Vivo (Journal of Pharmacology and Experimental Therapeutics, 2006)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H301: Toxic if swallowed
Danger Acute toxicity, oral - Category 3 - H319: Causes serious eye irritation
Warning Serious eye damage/eye irritation - Category 2A - H371: May cause damage to organs
Warning Specific target organ toxicity, single exposure - Category 2 - Succivil
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SMILESC1=CC=C2C(=O)C=CC(=O)C2=C1
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InChIKeyFRASJONUBLZVQX-UHFFFAOYSA-N
- Pubchem - 1,4-NAPHTHOQUINONE
- Wikipedia - 1,4-naphthoquinone
1,4-Naphthoquinone or para-naphthoquinone is an organic compound derived from naphthalene. Several isomeric naphthoquinones are known, notably 1,2-naphthoquinone. 1,4-Naphthoquinone forms volatile yellow triclinic crystals and has a sharp odor similar to benzoquinone.
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Similar Compounds
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