| Weight | 189.17 g/mol |
|---|---|
| Formula | C10H7NO3 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 1 |
kynurenic acid (13593-94-7, 492-27-3)
Kynurenate
Score:
#587 in Neuroscience
,
#1006 in Biochemistry
,
#2644 in Biology
,
#3301 in Chemistry
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- Sigma-Aldrich - kynurenic acid14.90 - 119.00 USD
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- The Brain Metabolite Kynurenic Acid Inhibits 7 Nicotinic Receptor Activity and Increases Non-7 Nicotinic Receptor Expression: Physiopathological Implications (The Journal of Neuroscience, 2001)
- Increased cortical kynurenate content in schizophrenia. (Biological Psychiatry, 2001)
- Kynurenic acid blocks neurotoxicity and seizures induced in rats by the related brain metabolite quinolinic acid (Neuroscience Letters, 1984)
- Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia (Neuroscience Letters, 2001)
- Kynurenic Acid as a Ligand for Orphan G Protein-coupled Receptor GPR35 (Journal of Biological Chemistry, 2006)
- Excitatory amino acid antagonists (kynurenic acid and MK-801) attenuate the development of morphine tolerance in the rat (Brain Research, 1991)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Kynurenate
-
SMILESC1=CC=C2C(=C1)C(=O)C=C(N2)C(=O)O
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InChIKeyHCZHHEIFKROPDY-UHFFFAOYSA-N
- Pubchem - kynurenic acid
- Wikipedia - kynurenic acid
Kynurenic acid (KYNA or KYN) is a product of the normal metabolism of amino acid L-tryptophan. It has been shown that kynurenic acid possesses neuroactive activity. It acts as an antiexcitotoxic and anticonvulsant, most likely through acting as an antagonist at excitatory amino acid receptors.
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kynurenic acid
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