| Weight | 308.772 g/mol |
|---|---|
| Formula | C17H13ClN4 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 4 |
| Rotatable Bonds | 3 |
Liarozole (115575-11-6)
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- LIAROZOLE ACTS SYNERGISTICALLY WITH 1ALPHA , 25-DIHYDROXYVITAMIN D3 TO INHIBIT GROWTH OF DU 145 HUMAN PROSTATE CANCER CELLS BY BLOCKING 24-HYDROXYLASE ACTIVITY (Endocrinology, 1999)
- Liarozole, an inhibitor of retinoic acid metabolism, exerts retinoid-mimetic effects in vivo. (Journal of Pharmacology and Experimental Therapeutics, 1992)
- Effects of Liarozole, a New Antitumoral Compound, on Retinoic Acid-induced Inhibition of Cell Growth and on Retinoic Acid Metabolism in MCF-7 Human Breast Cancer Cells (Cancer Research, 1992)
- Ketoconazole and liarozole in the treatment of advanced prostatic cancer. (Cancer, 1993)
- Modulation of all-trans retinoic acid pharmacokinetics by liarozole (Cancer Chemotherapy and Pharmacology, 1994)
- Oral liarozole in the treatment of palmoplantar pustular psoriasis: A randomized, double-blind, placebo-controlled study (British Journal of Dermatology, 2001)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=CC(=CC(=C1)Cl)C(C2=CC3=C(C=C2)N=CN3)N4C=CN=C4
-
InChIKeyUGFHIPBXIWJXNA-UHFFFAOYSA-N
- Pubchem - Liarozole
- Wikipedia - liarozole
Liarozole is a retinoic acid metabolism-blocking drug and aromatase inhibitor.
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