| Weight | 205.348 g/mol |
|---|---|
| Formula | C8H15NOS2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 5 |
lipoamide (940-69-2, 3206-73-3)
lipamide · lipoamide, (+-)-isomer · 1,2-dithiolane-3-valeramide
Score:
#1282 in Biochemistry
,
#3149 in Biology
,
#3942 in Chemistry
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- The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductase from Escherichia coli (Proceedings of the National Academy of Sciences of the United States of America, 1997)
- 2-and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: Synthesis and correlation between redox cycling activities and in vitro cytotoxicity (Journal of Medicinal Chemistry, 2001)
- Nucleotide sequence of the lipoamide dehydrogenase gene of Escherichia coli K12 (FEBS Journal, 1983)
- Efficient reduction of lipoamide and lipoic acid by mammalian thioredoxin reductase. (Biochemical and Biophysical Research Communications, 1996)
- Refined crystal structure of lipoamide dehydrogenase from Azotobacter vinelandii at 2.2 A resolution. A comparison with the structure of glutathione reductase. (Journal of Molecular Biology, 1991)
- Zinc is a potent inhibitor of thiol oxidoreductase activity and stimulates reactive oxygen species production by lipoamide dehydrogenase. (Journal of Biological Chemistry, 2002)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - lipamide
- lipoamide, (+-)-isomer
- 1,2-dithiolane-3-valeramide
- 6,8-thioctic amide
- alpha-lipoic amide
-
SMILESC1CSSC1CCCCC(=O)N
-
InChIKeyFCCDDURTIIUXBY-UHFFFAOYSA-N
- Pubchem - lipoamide
- Wikipedia - (R)-lipoamide
Lipoamide is a trivial name for 6,8-dithiooctanoic amide. It is 6,8-dithiooctanoic acid's functional form where the carboxyl group is attached to protein (or any other amine) by an amide linkage (containing -NH2). Sometimes lipoamide is used to refer to protein bound lipoic acid, but this can be misleading as this is technically incorrect.
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lipoamide
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